Biomedical applications of Jones-matrix tomography to polycrystalline films of biological fluids

V. A. Ushenko, A. Yu Sdobnov, W. D. Mishalov, A. V. Dubolazov, O. V. Olar, V. T. Bachinskyi, A. G. Ushenko, Yu A. Ushenko, O. Ya Wanchuliak, I. Meglinski*

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Algorithms for reconstruction of linear and circular birefringence-dichroism of optically thin anisotropic biological layers are presented. The technique of Jones-matrix tomography of polycrystalline films of biological fluids of various human organs has been developed and experimentally tested. The coordinate distributions of phase and amplitude anisotropy of bile films and synovial fluid taken from the knee joint are determined and statistically analyzed. Criteria (statistical moments of 3rd and 4th orders) of differential diagnostics of early stages of cholelithiasis and septic arthritis of the knee joint with excellent balanced accuracy were determined. Data on the diagnostic efficiency of the Jones-matrix tomography method for polycrystalline plasma (liver disease), urine (albuminuria) and cytological smears (cervical cancer) are presented.

Original languageEnglish
Article number1950017
JournalJournal of Innovative Optical Health Sciences
Volume12
Issue number6
Early online date23 Jul 2019
DOIs
Publication statusPublished - 1 Nov 2019

Bibliographical note

This is an Open Access article published by World Scienti¯c Publishing Company. It is distributed under the terms of the Creative
Commons Attribution 4.0 (CC BY) License which permits use, distribution and reproduction in any medium, provided the original
work is properly cited.

Keywords

  • Fourier optics and signal processing
  • imaging systems
  • medical and biological imaging
  • Polarization

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    Ushenko, V. A., Sdobnov, A. Y., Mishalov, W. D., Dubolazov, A. V., Olar, O. V., Bachinskyi, V. T., Ushenko, A. G., Ushenko, Y. A., Wanchuliak, O. Y., & Meglinski, I. (2019). Biomedical applications of Jones-matrix tomography to polycrystalline films of biological fluids. Journal of Innovative Optical Health Sciences, 12(6), [1950017]. https://doi.org/10.1142/S1793545819500172