Eukaryotic cells having upregulated BMS1 genes and a nucleotide sequence encoding a recombinant protein or fragment for the production of such proteins or fragments are provided. This is based on the finding that elevated BMS1 levels, improve yields of recombinant proteins. Methods of producing recombinant proteins using such cells are also provided.
|Patent number||GB 0813253.2|
|Publication status||Published - 17 Jul 2008|
Bonander, N., Darby, R., Bill, R., & Grgic, L. (2008). IPC No. C12N1/19. BMS1 protein expression system. (Patent No. GB 0813253.2). http://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20120419&DB=EPODOC&locale=en_EP&CC=US&NR=2012094294A1&KC=A1&ND=4