Can you tell your clunis from your cubitus? A benchmark for functional imaging

Alison E. Fisher, Gareth R. Barnes*, Arjan Hillebrand, Caroline Burrow, Paul L. Furlong, Ian E. Holliday

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Advances in functional brain imaging have allowed the development of new investigative techniques with clinical application—ranging from presurgical mapping of eloquent cortex to identifying cortical regions involved in religious experiences. Similarly a variety of methods are available to referring physicians, ranging from metabolic measures such as functional magnetic resonance imaging and positron emission tomography to measurements based on electrical activity such as electroencephalography and magnetoencephalography. However, there are no universal benchmarks by which to judge between these methods. In this study we attempt to develop a standard for functional localisation, based on the known functional organisation of somatosensory cortex. Studies have shown spatially distinct sites of brain activity in response to stimulation of various body parts. Generally these studies have focused on areas with large cortical representations, such as the index finger and face. We tested the limits of magnetoencephalography source localisation by stimulation of body parts, namely the clunis and the cubitus, that map to proximal and relatively poorly represented regions of somatosensory cortex.
Original languageEnglish
Pages (from-to)1492-1493
Number of pages2
JournalBMJ
Volume329
Issue number7480
DOIs
Publication statusPublished - 18 Dec 2004

Bibliographical note

Copyright © 2004, BMJ Publishing Group Ltd.

Keywords

  • functional brain imaging
  • presurgical mapping
  • eloquent cortex
  • religious experiences
  • metabolic measures
  • functional magnetic resonance imaging
  • positron emission tomography
  • electrical activity
  • electroencephalography
  • magnetoencephalography
  • standard
  • functional localisation
  • somatosensory cortex

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