Abstract
Halide octahedral molybdenum clusters [(Mo6X8)L6]n- possess luminescence properties that are highly promising for biological applications. These properties are rather dependent on the nature of both the inner ligands X (i.e. Cl, Br, or I) and the apical organic or inorganic ligands L. Herein, the luminescence properties and the toxicity of thiol-modified polystyrene microbeads (PS-SH) doped with [(Mo6X8)(NO3)6]2- (X=Cl, Br, I) were studied and evaluated using human epidermoid larynx carcinoma (Hep2) cell cultures. According to our data, the photoluminescence quantum yield of (Mo6I8)@PS-SH is significantly higher (0.04) than that of (Mo6Cl8)@PS-SH (6Br8)@PS-SH (6X8)@PS-SH showed that all three types of doped microbeads had no significant effect on the viability and proliferation of the cells.
Original language | English |
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Pages (from-to) | 922– 928 |
Number of pages | 7 |
Journal | Polymers for Advanced Technologies |
Volume | 27 |
Issue number | 7 |
Early online date | 11 Jan 2016 |
DOIs | |
Publication status | Published - 13 Jun 2016 |
Bibliographical note
This is the peer reviewed version of the following article: Vorotnikova, N. A., Efremova, O. A., Tsygankova, A. R., Brylev, K. A., Edeleva, M. V., Kurskaya, O. G., ... Shestopalov, M. A. (2016). Characterization and cytotoxicity studies of thiol-modified polystyrene microbeads doped with [(Mo6X8)(NO3)6]2- (X=Cl, Br, I). Polymers for advanced technologies, Early view., which has been published in final form at http://dx.doi.org/10.1002/pat.3749. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.Funding: Russian Science Foundation (14-14-00192); Royal Society (IE140281); and FP7 Marie Curie Inter-European Fellowship (327440)
Keywords
- cytotoxicity
- molybdenum cluster complex
- photoluminescence
- polystyrene microbeads