Chemical and biological approaches to glycoprotein synthesis

R M Bill; S L Flitsch

doi:10.1016/S1074-5521(96)90255-0

Chemical and biological approaches to glycoprotein synthesis

R M Bill
, S L Flitsch

Research output: Contribution to journal › Article › peer-review

45 Citations (Scopus)

Abstract

Protein glycosylation is a common posttranslational modification that produces glycoproteins that are highly complex in terms of both their structure and in their function. Systematic structure-function studies of such glycoproteins require synthetic methods that can produce homogeneous glycoproteins with defined oligosaccharide sidechains.

Original language	English
Pages (from-to)	145-9
Number of pages	5
Journal	Chemistry and Biology
Volume	3
Issue number	3
DOIs	https://doi.org/10.1016/S1074-5521(96)90255-0
Publication status	Published - Mar 1996

Keywords

Glycoproteins
Glycosylation
Oligosaccharides

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10.1016/S1074-5521(96)90255-0

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title = "Chemical and biological approaches to glycoprotein synthesis",

abstract = "Protein glycosylation is a common posttranslational modification that produces glycoproteins that are highly complex in terms of both their structure and in their function. Systematic structure-function studies of such glycoproteins require synthetic methods that can produce homogeneous glycoproteins with defined oligosaccharide sidechains.",

keywords = "Glycoproteins, Glycosylation, Oligosaccharides",

author = "Bill, \{R M\} and Flitsch, \{S L\}",

year = "1996",

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T1 - Chemical and biological approaches to glycoprotein synthesis

AU - Bill, R M

AU - Flitsch, S L

PY - 1996/3

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N2 - Protein glycosylation is a common posttranslational modification that produces glycoproteins that are highly complex in terms of both their structure and in their function. Systematic structure-function studies of such glycoproteins require synthetic methods that can produce homogeneous glycoproteins with defined oligosaccharide sidechains.

AB - Protein glycosylation is a common posttranslational modification that produces glycoproteins that are highly complex in terms of both their structure and in their function. Systematic structure-function studies of such glycoproteins require synthetic methods that can produce homogeneous glycoproteins with defined oligosaccharide sidechains.

KW - Glycoproteins

KW - Glycosylation

KW - Oligosaccharides

UR - http://www.sciencedirect.com/science/article/pii/S1074552196902550

U2 - 10.1016/S1074-5521(96)90255-0

DO - 10.1016/S1074-5521(96)90255-0

M3 - Article

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SN - 1074-5521

VL - 3

SP - 145

EP - 149

JO - Chemistry and Biology

JF - Chemistry and Biology

IS - 3

ER -

Chemical and biological approaches to glycoprotein synthesis

Abstract

Keywords

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