Cholecystokinin-2/gastrin antagonists: 5-hydroxy-5-aryl-pyrrol-2-ones as anti-inflammatory analgesics for the treatment of inflammatory bowel disease

Keyphrases

• Cholecystokinin 100%
• CCK2 100%
• Aryl 100%
• Analgesic 100%
• Inflammatory Bowel Disease 100%
• Gastrin 100%
• Pyrrol-2-ones 100%
• Inflammation 50%
• IC50 50%
• Binding Assay 50%
• Indomethacin 50%
• Anti-inflammatory Activity 50%
• Mucochloric Acid 50%
• Isolated Tissue 50%
• Antagonism 50%
• In Vivo Evaluation 50%
• Tramadol 50%
• Analgesic Effect 50%
• Selective Ligands 50%
• Tissue Preparation 50%
• Selective Antagonist 50%
• Dextran Sulfate Sodium 50%
• Hot Plate 50%
• GI Protection 50%
• Prednisolone 50%
• Analgesic Activity 50%
• Formalin Test 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Cholecystokinin 100%
• Anti-Inflammatory Drug 100%
• Analgesic Agent 100%
• Inflammatory Bowel Disease 100%
• Cholecystokinin B Receptor Antagonist 100%
• Inflammation 33%
• IC50 33%
• Indometacin 33%
• Tramadol 33%
• Dextran Sulfate 33%
• Formaldehyde 33%
• Ulcer 33%
• Prednisolone 33%