Chondroblastoma in pelvis and extremities- a signle centre study of 177 cases

M.k. Laitinen, J.d. Stevenson, S. Evans, A. Abudu, V. Sumathi, L.m. Jeys, M.c. Parry

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Abstract

Introduction
Chondroblastoma is a rare benign bone tumour that usually occurs in children and young adults. They are cartilaginous tumours arising in the epiphysis or apophysis of a long bone. The tumour is classified as benign, although rare cases of pulmonary metastases have been reported. The aims of this study were to describe clinical, radiographic characteristics of chondroblastoma; to analyse the local recurrence rate and complications associated with surgery.

Material and methods
This retrospective study included 177 patients, who had been diagnosed with a chondroblastoma in extremity between 1990 and 2015.

Results
The most common site was proximal tibia 20%, followed by proximal humerus 19%, proximal femur 18%, distal femur 16% and foot 15%. One patient has died of the disease and one patient is alive after being operated for lung metastases. There was local recurrence in 25/177 (14%) patients. The median time to local recurrence was 10 months (range 3-158 months). The most common site for local recurrence was proximal tibia (22.2%). The proximal femur was the location in 32/178 (18%) of the cases. 18/32 (56%) were in the greater trochanter and 14/32 (44%) in the femoral head. The mean age was lower in tumours located in femoral head when compared to the greater trochanter; 19.5 years and 13.9 years respectively (p=0.004). Tumours located in greater trochanter were all curetted without further complications. Local recurrence was seen more often in femoral head tumours, though without statistical significance; 3/14 (21%) and none, respectively (p=0.073).

Conclusions
Chondroblastoma is a rare benign to intermediate grade bone tumour with a potential to metastasise. Femoral head chondroblastoma is rare, presenting 4.5% of all chondroblastoma cases. Around 50% of the chondroblastoma in femoral head. occur in patients with open growth plates.
Original languageEnglish
Article number100248
Pages (from-to)100248
JournalJournal of Bone Oncology
Volume17
Early online date27 Jun 2019
DOIs
Publication statusPublished - 1 Aug 2019

Bibliographical note

Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

Keywords

  • Bone neoplasm
  • Chondroblastoma
  • Femur head
  • Growth plate

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    Laitinen, M. K., Stevenson, J. D., Evans, S., Abudu, A., Sumathi, V., Jeys, L. M., & Parry, M. C. (2019). Chondroblastoma in pelvis and extremities- a signle centre study of 177 cases. Journal of Bone Oncology, 17, 100248. [100248]. https://doi.org/10.1016/j.jbo.2019.100248