Cognitive function, gait, and gait variability in older people

a population-based study

Kara L. Martin, Leigh Blizzard, Amanda G. Wood, Velandai Srikanth, Russell Thomson, Lauren M. Sanders, Michele L. Callisaya

Research output: Contribution to journalArticle

Abstract

Background. Gait impairments are associated with falls and loss of independence. The study of factors associated with poorer gait may assist in developing methods to preserve mobility in older people. The aim of this study was to examine the associations between a range of cognitive functions and gait and gait variability in a population-based sample of older people.
Methods. Gait and intra-individual gait variability measures were obtained using the GAITRite walkway in a sample of older people, aged 60–85 years (N = 422), randomly selected from the Tasmanian electoral roll. Raw scores from a cognitive battery were subjected to principal component analyses deriving four summary domains: executive function/attention, processing speed, memory, and visuospatial ability. Multivariable linear regression was used to examine associations between cognitive domains and gait measures adjusting for age, sex, ambulatory activity, medication use, and mood.
Results. The mean age of the sample was 72.0 years (SD = 7.0), with 238 men (56%). Poorer executive function was independently associated with poorer performance in most absolute gait measures and with greater variability in double support phase and step time. Processing speed was associated with absolute gait measures and double support phase variability. Visuospatial ability was only associated with greater double support phase variability, independently of executive function and processing speed. Memory was not independently associated with any gait measure.
Conclusions. In community-dwelling older people, executive function/attention and processing speed were associated with many aspects of gait, whereas visuospatial ability may only play a role in double support phase variability.
Original languageEnglish
Pages (from-to)726-732
Number of pages7
JournalJournals of Gerontology: Series A
Volume68
Issue number6
DOIs
Publication statusPublished - Jun 2013

Fingerprint

Gait
Cognition
Population
Executive Function
Aptitude
Independent Living
Principal Component Analysis
Linear Models

Keywords

  • gait
  • gait variability
  • cognitive function
  • aging

Cite this

Martin, K. L., Blizzard, L., Wood, A. G., Srikanth, V., Thomson, R., Sanders, L. M., & Callisaya, M. L. (2013). Cognitive function, gait, and gait variability in older people: a population-based study. Journals of Gerontology: Series A, 68(6), 726-732. https://doi.org/10.1093/gerona/gls224
Martin, Kara L. ; Blizzard, Leigh ; Wood, Amanda G. ; Srikanth, Velandai ; Thomson, Russell ; Sanders, Lauren M. ; Callisaya, Michele L. / Cognitive function, gait, and gait variability in older people : a population-based study. In: Journals of Gerontology: Series A. 2013 ; Vol. 68, No. 6. pp. 726-732.
@article{12b4a6f341d740b0b376e0924fdb83cc,
title = "Cognitive function, gait, and gait variability in older people: a population-based study",
abstract = "Background. Gait impairments are associated with falls and loss of independence. The study of factors associated with poorer gait may assist in developing methods to preserve mobility in older people. The aim of this study was to examine the associations between a range of cognitive functions and gait and gait variability in a population-based sample of older people. Methods. Gait and intra-individual gait variability measures were obtained using the GAITRite walkway in a sample of older people, aged 60–85 years (N = 422), randomly selected from the Tasmanian electoral roll. Raw scores from a cognitive battery were subjected to principal component analyses deriving four summary domains: executive function/attention, processing speed, memory, and visuospatial ability. Multivariable linear regression was used to examine associations between cognitive domains and gait measures adjusting for age, sex, ambulatory activity, medication use, and mood. Results. The mean age of the sample was 72.0 years (SD = 7.0), with 238 men (56{\%}). Poorer executive function was independently associated with poorer performance in most absolute gait measures and with greater variability in double support phase and step time. Processing speed was associated with absolute gait measures and double support phase variability. Visuospatial ability was only associated with greater double support phase variability, independently of executive function and processing speed. Memory was not independently associated with any gait measure. Conclusions. In community-dwelling older people, executive function/attention and processing speed were associated with many aspects of gait, whereas visuospatial ability may only play a role in double support phase variability.",
keywords = "gait, gait variability, cognitive function, aging",
author = "Martin, {Kara L.} and Leigh Blizzard and Wood, {Amanda G.} and Velandai Srikanth and Russell Thomson and Sanders, {Lauren M.} and Callisaya, {Michele L.}",
year = "2013",
month = "6",
doi = "10.1093/gerona/gls224",
language = "English",
volume = "68",
pages = "726--732",
journal = "Journals of Gerontology: Series A",
issn = "1079-5006",
publisher = "Oxford University Press",
number = "6",

}

Martin, KL, Blizzard, L, Wood, AG, Srikanth, V, Thomson, R, Sanders, LM & Callisaya, ML 2013, 'Cognitive function, gait, and gait variability in older people: a population-based study', Journals of Gerontology: Series A, vol. 68, no. 6, pp. 726-732. https://doi.org/10.1093/gerona/gls224

Cognitive function, gait, and gait variability in older people : a population-based study. / Martin, Kara L.; Blizzard, Leigh; Wood, Amanda G.; Srikanth, Velandai; Thomson, Russell; Sanders, Lauren M.; Callisaya, Michele L.

In: Journals of Gerontology: Series A, Vol. 68, No. 6, 06.2013, p. 726-732.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Cognitive function, gait, and gait variability in older people

T2 - a population-based study

AU - Martin, Kara L.

AU - Blizzard, Leigh

AU - Wood, Amanda G.

AU - Srikanth, Velandai

AU - Thomson, Russell

AU - Sanders, Lauren M.

AU - Callisaya, Michele L.

PY - 2013/6

Y1 - 2013/6

N2 - Background. Gait impairments are associated with falls and loss of independence. The study of factors associated with poorer gait may assist in developing methods to preserve mobility in older people. The aim of this study was to examine the associations between a range of cognitive functions and gait and gait variability in a population-based sample of older people. Methods. Gait and intra-individual gait variability measures were obtained using the GAITRite walkway in a sample of older people, aged 60–85 years (N = 422), randomly selected from the Tasmanian electoral roll. Raw scores from a cognitive battery were subjected to principal component analyses deriving four summary domains: executive function/attention, processing speed, memory, and visuospatial ability. Multivariable linear regression was used to examine associations between cognitive domains and gait measures adjusting for age, sex, ambulatory activity, medication use, and mood. Results. The mean age of the sample was 72.0 years (SD = 7.0), with 238 men (56%). Poorer executive function was independently associated with poorer performance in most absolute gait measures and with greater variability in double support phase and step time. Processing speed was associated with absolute gait measures and double support phase variability. Visuospatial ability was only associated with greater double support phase variability, independently of executive function and processing speed. Memory was not independently associated with any gait measure. Conclusions. In community-dwelling older people, executive function/attention and processing speed were associated with many aspects of gait, whereas visuospatial ability may only play a role in double support phase variability.

AB - Background. Gait impairments are associated with falls and loss of independence. The study of factors associated with poorer gait may assist in developing methods to preserve mobility in older people. The aim of this study was to examine the associations between a range of cognitive functions and gait and gait variability in a population-based sample of older people. Methods. Gait and intra-individual gait variability measures were obtained using the GAITRite walkway in a sample of older people, aged 60–85 years (N = 422), randomly selected from the Tasmanian electoral roll. Raw scores from a cognitive battery were subjected to principal component analyses deriving four summary domains: executive function/attention, processing speed, memory, and visuospatial ability. Multivariable linear regression was used to examine associations between cognitive domains and gait measures adjusting for age, sex, ambulatory activity, medication use, and mood. Results. The mean age of the sample was 72.0 years (SD = 7.0), with 238 men (56%). Poorer executive function was independently associated with poorer performance in most absolute gait measures and with greater variability in double support phase and step time. Processing speed was associated with absolute gait measures and double support phase variability. Visuospatial ability was only associated with greater double support phase variability, independently of executive function and processing speed. Memory was not independently associated with any gait measure. Conclusions. In community-dwelling older people, executive function/attention and processing speed were associated with many aspects of gait, whereas visuospatial ability may only play a role in double support phase variability.

KW - gait

KW - gait variability

KW - cognitive function

KW - aging

UR - https://academic.oup.com/biomedgerontology/article-lookup/doi/10.1093/gerona/gls224

U2 - 10.1093/gerona/gls224

DO - 10.1093/gerona/gls224

M3 - Article

VL - 68

SP - 726

EP - 732

JO - Journals of Gerontology: Series A

JF - Journals of Gerontology: Series A

SN - 1079-5006

IS - 6

ER -