Abstract
We introduce a noninvasive diagnostic approach for functional monitoring of blood microflows in capillaries and thermoregulatory vessels within the skin. The measuring system is based on the combined use of laser Doppler flowmetry and skin contact thermometry. The obtained results suggest that monitoring of blood microcirculation during the occlusion, performed in conjunction with the skin temperature measurements in the thermally stabilized medium, has a great potential for quantitative assessment of angiospatic dysfunctions of the peripheral blood vessels. The indices of blood flow reserve and temperature response were measured and used as the primarily parameters of the functional diagnostics of the peripheral vessels of skin. Utilizing these parameters, a simple phenomenological model has been suggested to identify patients with angiospastic violations in the vascular system.
| Original language | English |
|---|---|
| Article number | 040502 |
| Journal | Journal of Biomedical Optics |
| Volume | 22 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 11 Apr 2017 |
Funding
The work was supported by a grant from the President of the Russian Federation for state support of young Russian scientists No. MK-7168.2016.8. The authors acknowledge the support of the Academy of Finland (Grant Nos: 296408 and 290596). Professor Meglinski also acknowledges partial support provided by the Russian Science Foundation project No. 15-14-10008.
Keywords
- blood microcirculation
- laser Doppler flowmetry
- occlusion
- rheumatology
- thermometry
- vasospastic disorders