Abstract
This paper introduces a compact, tunable femtosecond laser based on an Erbium-doped fiber, utilizing the Self-Soliton Frequency Shifted technique and PPLN crystal as a Second Harmonic Generation module. Achieving an unparalleled frequency conversion efficiency up to 55% for the 800 - 850 nm wavelength range, this compact laser emits sub-100 fs pulses. The laser operates simultaneously within the first and third biological windows, delivering pulse energies of 10.4 nJ and 5.1 nJ, respectively. This performance, previously unattained in similar systems, is achieved while maintaining Second Harmonic Generation power stability below 2% RMS. The presented compact laser, developed for bladder cancer detection through multiphoton microscopy, will significantly improve the system’s compactness, precision, and cancer detection efficiency.
| Original language | English |
|---|---|
| Article number | 18867 |
| Number of pages | 8 |
| Journal | Scientific Reports |
| Volume | 15 |
| Issue number | 1 |
| Early online date | 29 May 2025 |
| DOIs | |
| Publication status | Published - 29 May 2025 |
Bibliographical note
Copyright © The Author(s) 2025. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/Funding
The authors acknowledge the support of the EPSRC project EP/W002868/1 and the European Union’s Horizon 2020 research and innovation programme under Grant Agreement 871277.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
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