Comparison of biomechanical parameters in penetrating keratoplasty and normal eyes using the Ocular Response Analyser

Mohammed Laiquzzaman, Katya Tambe, Sunil Shah*

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Background: To compare corneal hysteresis (CH) and corneal resistance factor (CRF) in eyes 1 year following penetrating keratoplasty (PK) with that of normal eyes using the Ocular Response Analyser.Methods: Prospective case comparison of 166 normal right eyes and 34 unilateral post-PK eyes presenting to a teaching hospital in Birmingham, UK. The CH, CRF and Goldmann-correlated intraocular pressure, of each eye was measured using the Ocular Response Analyser. The central corneal thickness (CCT) was measured using an ultrasonic pachymeter.Results: The mean CH was 10.6 ±2.0 mmHg, standard deviation (SD) and CRF was 10.2 ± 2.0 mmHg (SD) in normal eyes and 8.9 ± 3.3 mmHg and 8.1 ± 3.3 mmHg in post-PK eyes, respectively. The mean CCT was 541.8 ± 36.1 μm in normal eyes and 556.0 ±69.2 μm in post-PK eyes. The Goldmann-correlated intraocular pressure was 16.1 ± 3.1 mmHg and 12.4 ± 2.9 mmHg in normal eyes and post-PK eyes, respectively. The CCT was found to be higher in post-PK eyes compared with normal eyes but the difference was not statistically significant (P > 0.5).Conclusion: Reduced biomechanical measures were found in post-PK eyes despite a higher mean CCT. This may be due to the altered corneal structure following PK.

Original languageEnglish
Pages (from-to)758-763
Number of pages6
JournalClinical and Experimental Ophthalmology
Volume38
Issue number8
DOIs
Publication statusPublished - Nov 2010

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Penetrating Keratoplasty
R Factors
Intraocular Pressure

Keywords

  • corneal resistance factor
  • hysteresis
  • penetrating keratoplasty

Cite this

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abstract = "Background: To compare corneal hysteresis (CH) and corneal resistance factor (CRF) in eyes 1 year following penetrating keratoplasty (PK) with that of normal eyes using the Ocular Response Analyser.Methods: Prospective case comparison of 166 normal right eyes and 34 unilateral post-PK eyes presenting to a teaching hospital in Birmingham, UK. The CH, CRF and Goldmann-correlated intraocular pressure, of each eye was measured using the Ocular Response Analyser. The central corneal thickness (CCT) was measured using an ultrasonic pachymeter.Results: The mean CH was 10.6 ±2.0 mmHg, standard deviation (SD) and CRF was 10.2 ± 2.0 mmHg (SD) in normal eyes and 8.9 ± 3.3 mmHg and 8.1 ± 3.3 mmHg in post-PK eyes, respectively. The mean CCT was 541.8 ± 36.1 μm in normal eyes and 556.0 ±69.2 μm in post-PK eyes. The Goldmann-correlated intraocular pressure was 16.1 ± 3.1 mmHg and 12.4 ± 2.9 mmHg in normal eyes and post-PK eyes, respectively. The CCT was found to be higher in post-PK eyes compared with normal eyes but the difference was not statistically significant (P > 0.5).Conclusion: Reduced biomechanical measures were found in post-PK eyes despite a higher mean CCT. This may be due to the altered corneal structure following PK.",
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Comparison of biomechanical parameters in penetrating keratoplasty and normal eyes using the Ocular Response Analyser. / Laiquzzaman, Mohammed; Tambe, Katya; Shah, Sunil.

In: Clinical and Experimental Ophthalmology, Vol. 38, No. 8, 11.2010, p. 758-763.

Research output: Contribution to journalArticle

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