Comparison of the influence of corneo-scleral and scleral lenses on ocular surface and tear film metrics in a presbyopic population

Edouard Lafosse; Daniel Monsálvez Romín; José-Juan Esteve-Taboada; James S Wolffsohn; Cristian Talens-Estarelles; Santiago García-Lázaro

doi:10.1016/j.clae.2017.09.014

Comparison of the influence of corneo-scleral and scleral lenses on ocular surface and tear film metrics in a presbyopic population

Edouard Lafosse, Daniel Monsálvez Romín, José-Juan Esteve-Taboada, James S Wolffsohn, Cristian Talens-Estarelles, Santiago García-Lázaro

Research output: Contribution to journal › Article › peer-review

Abstract

PURPOSE: To assess and compare the effect of the corneo-scleral lenses (C-ScL) and scleral lenses (ScL) on tear film parameters and central corneal thickness (CCT) in healthy presbyopic subjects.

METHODS: Thirty subjects wore two contact lenses (CLs), randomly assigned, of neutral power, but of different diameters, 12.7mm (C-ScL) and 18mm (ScL) and being equal in the others parameters: material (HS100) and centre thickness (0.29mm). At baseline, 20min after insertion and at 8h, the tear meniscus area (TMA) and CCT was measured (with optical coherence tomography) as well as tear osmolarity.

RESULTS: TMA revealed statistical differences for both lenses at 20min (p<0.001), and also at 8h (p=0.003), being greater for the C-ScL. CCT showed statistical differences for both lenses at 20min (p=0.002), and also at 8h (p=0.001), being lower for the C-ScL. Osmolarity did not reveal statistical differences at 20min (p=0.29), while it was statistically different at 8h (p=0.03), being lower for the C-ScL.

CONCLUSIONS: C-ScL lead to a lesser reduction in the TMA and a lower induced hypoxic stress than the ScL. Osmolarity levels remained within normal values across the day with no clinical difference between lenses. Both designs can represent a good optical platform for correcting presbyopia as well as protecting the ocular surface by vaulting the cornea.

Original language	English
Pages (from-to)	122-127
Journal	Contact Lens and Anterior Eye
Volume	41
Issue number	1
Early online date	28 Sept 2017
DOIs	https://doi.org/10.1016/j.clae.2017.09.014
Publication status	Published - 1 Feb 2018

Bibliographical note

© 2017, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International

Funding: uropean Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No.642760 EDEN ITN-EJD Project Horizon 2020

Keywords

Corneo-scleral lens
Scleral lens
Ocular surface
Presbyopia
Tear film

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10.1016/j.clae.2017.09.014

Comparison of the influence of corneo-scleral and scleral lenses on ocular surface and tear film metrics in a presbyopic population
© 2017, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Accepted author manuscript, 147 KBLicence: CC BY-NC-ND 3.0

Cite this

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title = "Comparison of the influence of corneo-scleral and scleral lenses on ocular surface and tear film metrics in a presbyopic population",

abstract = "PURPOSE: To assess and compare the effect of the corneo-scleral lenses (C-ScL) and scleral lenses (ScL) on tear film parameters and central corneal thickness (CCT) in healthy presbyopic subjects.METHODS: Thirty subjects wore two contact lenses (CLs), randomly assigned, of neutral power, but of different diameters, 12.7mm (C-ScL) and 18mm (ScL) and being equal in the others parameters: material (HS100) and centre thickness (0.29mm). At baseline, 20min after insertion and at 8h, the tear meniscus area (TMA) and CCT was measured (with optical coherence tomography) as well as tear osmolarity.RESULTS: TMA revealed statistical differences for both lenses at 20min (p<0.001), and also at 8h (p=0.003), being greater for the C-ScL. CCT showed statistical differences for both lenses at 20min (p=0.002), and also at 8h (p=0.001), being lower for the C-ScL. Osmolarity did not reveal statistical differences at 20min (p=0.29), while it was statistically different at 8h (p=0.03), being lower for the C-ScL.CONCLUSIONS: C-ScL lead to a lesser reduction in the TMA and a lower induced hypoxic stress than the ScL. Osmolarity levels remained within normal values across the day with no clinical difference between lenses. Both designs can represent a good optical platform for correcting presbyopia as well as protecting the ocular surface by vaulting the cornea.",

keywords = "Corneo-scleral lens, Scleral lens, Ocular surface, Presbyopia, Tear film",

author = "Edouard Lafosse and Rom{\'i}n, {Daniel Mons{\'a}lvez} and Jos{\'e}-Juan Esteve-Taboada and Wolffsohn, {James S} and Cristian Talens-Estarelles and Santiago Garc{\'i}a-L{\'a}zaro",

note = "{\textcopyright} 2017, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Funding: uropean Union{\textquoteright}s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No.642760 EDEN ITN-EJD Project Horizon 2020",

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day = "1",

doi = "10.1016/j.clae.2017.09.014",

language = "English",

volume = "41",

pages = "122--127",

journal = "Contact Lens and Anterior Eye",

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TY - JOUR

T1 - Comparison of the influence of corneo-scleral and scleral lenses on ocular surface and tear film metrics in a presbyopic population

AU - Lafosse, Edouard

AU - Romín, Daniel Monsálvez

AU - Esteve-Taboada, José-Juan

AU - Wolffsohn, James S

AU - Talens-Estarelles, Cristian

AU - García-Lázaro, Santiago

N1 - © 2017, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Funding: uropean Union’s Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No.642760 EDEN ITN-EJD Project Horizon 2020

PY - 2018/2/1

Y1 - 2018/2/1

N2 - PURPOSE: To assess and compare the effect of the corneo-scleral lenses (C-ScL) and scleral lenses (ScL) on tear film parameters and central corneal thickness (CCT) in healthy presbyopic subjects.METHODS: Thirty subjects wore two contact lenses (CLs), randomly assigned, of neutral power, but of different diameters, 12.7mm (C-ScL) and 18mm (ScL) and being equal in the others parameters: material (HS100) and centre thickness (0.29mm). At baseline, 20min after insertion and at 8h, the tear meniscus area (TMA) and CCT was measured (with optical coherence tomography) as well as tear osmolarity.RESULTS: TMA revealed statistical differences for both lenses at 20min (p<0.001), and also at 8h (p=0.003), being greater for the C-ScL. CCT showed statistical differences for both lenses at 20min (p=0.002), and also at 8h (p=0.001), being lower for the C-ScL. Osmolarity did not reveal statistical differences at 20min (p=0.29), while it was statistically different at 8h (p=0.03), being lower for the C-ScL.CONCLUSIONS: C-ScL lead to a lesser reduction in the TMA and a lower induced hypoxic stress than the ScL. Osmolarity levels remained within normal values across the day with no clinical difference between lenses. Both designs can represent a good optical platform for correcting presbyopia as well as protecting the ocular surface by vaulting the cornea.

AB - PURPOSE: To assess and compare the effect of the corneo-scleral lenses (C-ScL) and scleral lenses (ScL) on tear film parameters and central corneal thickness (CCT) in healthy presbyopic subjects.METHODS: Thirty subjects wore two contact lenses (CLs), randomly assigned, of neutral power, but of different diameters, 12.7mm (C-ScL) and 18mm (ScL) and being equal in the others parameters: material (HS100) and centre thickness (0.29mm). At baseline, 20min after insertion and at 8h, the tear meniscus area (TMA) and CCT was measured (with optical coherence tomography) as well as tear osmolarity.RESULTS: TMA revealed statistical differences for both lenses at 20min (p<0.001), and also at 8h (p=0.003), being greater for the C-ScL. CCT showed statistical differences for both lenses at 20min (p=0.002), and also at 8h (p=0.001), being lower for the C-ScL. Osmolarity did not reveal statistical differences at 20min (p=0.29), while it was statistically different at 8h (p=0.03), being lower for the C-ScL.CONCLUSIONS: C-ScL lead to a lesser reduction in the TMA and a lower induced hypoxic stress than the ScL. Osmolarity levels remained within normal values across the day with no clinical difference between lenses. Both designs can represent a good optical platform for correcting presbyopia as well as protecting the ocular surface by vaulting the cornea.

KW - Corneo-scleral lens

KW - Scleral lens

KW - Ocular surface

KW - Presbyopia

KW - Tear film

UR - https://www.sciencedirect.com/science/article/pii/S1367048417302357?via%3Dihub

U2 - 10.1016/j.clae.2017.09.014

DO - 10.1016/j.clae.2017.09.014

M3 - Article

C2 - 28964684

SN - 1367-0484

VL - 41

SP - 122

EP - 127

JO - Contact Lens and Anterior Eye

JF - Contact Lens and Anterior Eye

IS - 1

ER -

Comparison of the influence of corneo-scleral and scleral lenses on ocular surface and tear film metrics in a presbyopic population

Abstract

Bibliographical note

Keywords

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