The study reports an advance in designing copper-based redox sensing MRI contrast agents. Although the data demonstrate that copper(II) complexes are not able to compete with lanthanoids species in terms of contrast, the redox-dependent switch between diamagnetic copper(I) and paramagnetic copper(II) yields a novel redox-sensitive contrast moiety with potential for reversibility.
|Number of pages||10|
|Early online date||9 Aug 2015|
|Publication status||Published - 2015|
Bibliographical noteThe final publication is available at Springer via http://dx.doi.org/10.1007/s10534-015-9875-3
Funding: BBSRC (BBS/B/01553).
Electronic supplementary material (doi: 10.1007/s10534-015-9875-3).
- copper macrocycles
- Redox sensitive contrast agent