Critical points in the pathway of antibiotic prescribing in a children’s hospital: the Antibiotic Mapping of Prescribing (ABMAP) study

Amreen Bashir, James Gray, Shahreen Bashir, Rabia Ahmed, Eirini Theodosiou

Research output: Contribution to journalArticlepeer-review

Abstract

Background

The WHO has identified Antimicrobial Resistance (AMR) as one of the most significant global risks facing modern medicine. Interventions to improve antibiotic prescribing have so far had limited impact.

Aim

To understand the barriers to effective antibiotic prescribing.

Methods

Mixed methodologies were used to investigate prescribing behaviours to identify the critical points in the antibiotic prescribing pathway for hospital inpatients. We assessed knowledge, experience or empowerment of prescribers, organisational factors and use of the laboratory. Phase 1 was an online survey to map barriers and facilitators to antibiotic prescribing (56 participants). Phase 2 consisted of focus groups and interviews to gain more understanding of prescribing behaviours (10 participants). Phase 3 was an online survey to obtain opinions on possible solutions (22 participants).

Results

Barriers to prescribing were: laboratory factors 71.6%, resource issues 40%, time constraints 17.5%, pressure from others 52%. Ninety-three percent of prescribers were concerned about AMR. In three scenarios only 9% were confident not to prescribe antibiotics for a patient without bacterial infection; 53% would prescribe unnecessarily broad spectrum antibiotics for pneumonia. Only 5% would de-escalate antibiotics in a microbiologically-confirmed bacteraemia.

Despite concerns about AMR, prescribers did not perceive continuing antibiotics for individual patients might promote resistance. Prescribers were unwilling to change antibiotics out of hours and reported they preferred professional support for antibiotic prescribing.

Conclusions

There was a marked disparity between prescribers self-reporting of prescribing behaviour and responses to clinical scenarios. It was not clear whether training alone would change behaviours. Prescribers desired a directive mechanism to support antibiotic prescribing and stewardship.
Original languageEnglish
JournalJournal of Hospital Infection
Early online date30 Jul 2018
DOIs
Publication statusE-pub ahead of print - 30 Jul 2018

Bibliographical note

© 2018, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/

Fingerprint Dive into the research topics of 'Critical points in the pathway of antibiotic prescribing in a children’s hospital: the Antibiotic Mapping of Prescribing (ABMAP) study'. Together they form a unique fingerprint.

Cite this