TY - JOUR
T1 - Decision support based on genomics
T2 - integration of data-and knowledge-driven reasoning
AU - Sfakianakis, S.
AU - Blazantonakis, M.
AU - Dimou, I.
AU - Zervakis, M.
AU - Tsiknakis, M.
AU - Potamias, G.
AU - Kafetzopoulos, D.
AU - Lowe, D.
PY - 2010
Y1 - 2010
N2 - The breadth and depth of available clinico-genomic information, present an enormous opportunity for improving our ability to study disease mechanisms and meet the individualised medicine needs. A difficulty occurs when the results are to be transferred 'from bench to bedside'. Diversity of methods is one of the causes, but the most critical one relates to our inability to share and jointly exploit data and tools. This paper presents a perspective on current state-of-the-art in the analysis of clinico-genomic data and its relevance to medical decision support. It is an attempt to investigate the issues related to data and knowledge integration.
AB - The breadth and depth of available clinico-genomic information, present an enormous opportunity for improving our ability to study disease mechanisms and meet the individualised medicine needs. A difficulty occurs when the results are to be transferred 'from bench to bedside'. Diversity of methods is one of the causes, but the most critical one relates to our inability to share and jointly exploit data and tools. This paper presents a perspective on current state-of-the-art in the analysis of clinico-genomic data and its relevance to medical decision support. It is an attempt to investigate the issues related to data and knowledge integration.
KW - bioinformatics
KW - clinico-genomic knowledge discovery
KW - decision support
KW - integration of data and knowledge
KW - personalised medicine
UR - http://www.scopus.com/inward/record.url?scp=78651594366&partnerID=8YFLogxK
UR - http://www.inderscience.com/info/inarticle.php?artid=32697
U2 - 10.1504/IJBET.2010.032697
DO - 10.1504/IJBET.2010.032697
M3 - Article
AN - SCOPUS:78651594366
SN - 1752-6418
VL - 3
SP - 287
EP - 307
JO - International Journal of Biomedical Engineering and Technology
JF - International Journal of Biomedical Engineering and Technology
IS - 3-4
ER -