Determinants of Maternal and Infant Omega-3 Status at 3 Months Postpartum: Findings from the APrON Longitudinal Cohort Study

Jaqueline Munhoz; Nour Wattar; Susan Goruk; Mohammadreza Pakseresht; Megan Jarman; Laura Forbes; Rhonda C Bell; Fatheema B Subhan; Catherine J Field

doi:10.1016/j.ajcnut.2025.01.002

Determinants of Maternal and Infant Omega-3 Status at 3 Months Postpartum: Findings from the APrON Longitudinal Cohort Study

Jaqueline Munhoz
, Nour Wattar
, Susan Goruk
, Mohammadreza Pakseresht
, Megan Jarman
, Laura Forbes
, Rhonda C Bell
, Fatheema B Subhan
, Catherine J Field

School of Psychology

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

14 Downloads (Pure)

Abstract

Omega-3 long chain polyunsaturated fatty acids (LCPUFAs) are important dietary components for maternal and infant health during pregnancy and lactation. This study investigated determinants of maternal and infant LCPUFAs status at three months postpartum and the relationship between maternal serum, mother's milk, and infant LCPUFAs. This cross-sectional study included mothers (n=1481) and their offspring (n=526) at three months postpartum from the APrON cohort. Maternal dietary intake (24-hour recall), blood samples from mothers and infants, and maternal milk were collected. Fatty acid composition (relative % of total fatty acids) was determined by gas-liquid chromatography. Linear regression analyses explored associations between diet, sociodemographic factors, and fatty acid status. In a multivariable-adjusted analysis, maternal total dietary intake (supplement + food) was positively associated with the percentage of docosahexaenoic acid (DHA, standardized(S) ß=0.394; ß=0.394; 95% CI: 0.192, 0.558; P

Original language	English
Pages (from-to)	629-642
Number of pages	14
Journal	American Journal of Clinical Nutrition
Volume	121
Issue number	3
Early online date	7 Jan 2025
DOIs	https://doi.org/10.1016/j.ajcnut.2025.01.002
Publication status	Published - Mar 2025

Bibliographical note

Crown Copyright © 2025 Published by Elsevier Inc. on behalf of American Society for Nutrition. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Data Access Statement

The data underlying in this article are available upon request to APrON Project Director (E-mail: [email protected]) or visit https://apronstudy.ca/contact-us/

Funding

The APrON cohort was funded by a grant from Alberta Innovates-Health Solutions (grant/award number N/A), The Dairy Farmers of Canada (RES0047122) and Alberta Canola Producers (ACPC 202FO16). CJF holds a Canadian Research Chair Tier 1 in Human Nutrition and Metabolism. JM received scholarships from Cancer Research Institute of Northern Alberta (CRINA), Alberta Graduate Excellence, Hazel McIntyre Summer Research Award and Dr. Elizabeth A Donald MSc Fellowship in human nutrition from the department of Agricultural, Food & Nutritional Science (University of Alberta, Edmonton, Alberta).

Keywords

fatty acids
dietary intake
human milk
lactation
docosahexaenoic acid

Access to Document

10.1016/j.ajcnut.2025.01.002Licence: CC BY-NC-ND 4.0

J Munhoz et al_Determinants of maternal and infant omega-3 status at 3 months postpartum_findings of APrON study
Crown Copyright © 2025 Published by Elsevier Inc. on behalf of American Society for Nutrition. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Final published version, 696 KBLicence: CC BY-NC-ND 4.0

Cite this

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title = "Determinants of Maternal and Infant Omega-3 Status at 3 Months Postpartum: Findings from the APrON Longitudinal Cohort Study",

abstract = "Omega-3 long chain polyunsaturated fatty acids (LCPUFAs) are important dietary components for maternal and infant health during pregnancy and lactation. This study investigated determinants of maternal and infant LCPUFAs status at three months postpartum and the relationship between maternal serum, mother's milk, and infant LCPUFAs. This cross-sectional study included mothers (n=1481) and their offspring (n=526) at three months postpartum from the APrON cohort. Maternal dietary intake (24-hour recall), blood samples from mothers and infants, and maternal milk were collected. Fatty acid composition (relative \% of total fatty acids) was determined by gas-liquid chromatography. Linear regression analyses explored associations between diet, sociodemographic factors, and fatty acid status. In a multivariable-adjusted analysis, maternal total dietary intake (supplement + food) was positively associated with the percentage of docosahexaenoic acid (DHA, standardized(S) {\ss}=0.394; {\ss}=0.394; 95\% CI: 0.192, 0.558; P",

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AU - Pakseresht, Mohammadreza

AU - Jarman, Megan

AU - Forbes, Laura

AU - Bell, Rhonda C

AU - Subhan, Fatheema B

AU - Field, Catherine J

N1 - Crown Copyright © 2025 Published by Elsevier Inc. on behalf of American Society for Nutrition. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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N2 - Omega-3 long chain polyunsaturated fatty acids (LCPUFAs) are important dietary components for maternal and infant health during pregnancy and lactation. This study investigated determinants of maternal and infant LCPUFAs status at three months postpartum and the relationship between maternal serum, mother's milk, and infant LCPUFAs. This cross-sectional study included mothers (n=1481) and their offspring (n=526) at three months postpartum from the APrON cohort. Maternal dietary intake (24-hour recall), blood samples from mothers and infants, and maternal milk were collected. Fatty acid composition (relative % of total fatty acids) was determined by gas-liquid chromatography. Linear regression analyses explored associations between diet, sociodemographic factors, and fatty acid status. In a multivariable-adjusted analysis, maternal total dietary intake (supplement + food) was positively associated with the percentage of docosahexaenoic acid (DHA, standardized(S) ß=0.394; ß=0.394; 95% CI: 0.192, 0.558; P

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Determinants of Maternal and Infant Omega-3 Status at 3 Months Postpartum: Findings from the APrON Longitudinal Cohort Study

Abstract

Bibliographical note

Data Access Statement

Funding

Keywords

Access to Document

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