TY - GEN
T1 - DiffKAN-Inpainting: KAN-Based Diffusion Model for Brain Tumor Inpainting
AU - Tao, Tianli
AU - Wang, Ziyang
AU - Zhang, Han
AU - Arvanitis, Theodoros N.
AU - Zhang, Le
PY - 2025/5/12
Y1 - 2025/5/12
N2 - Brain tumors delay the standard preprocessing workflow for further examination. Brain inpainting offers a viable, although difficult, solution for tumor tissue processing, which is necessary to improve the precision of the diagnosis and treatment. Most conventional U-Net-based generative models, however, often face challenges in capturing the complex, nonlinear latent representations inherent in brain imaging. In order to accomplish high-quality healthy brain tissue reconstruction, this work proposes DiffKAN-Inpainting, an innovative method that blends diffusion models with the Kolmogorov-Arnold Networks architecture. During the denoising process, we introduce the RePaint method and tumor information to generate images with a higher fidelity and smoother margin. Both qualitative and quantitative results demonstrate that as compared to the state-of-the-art methods, our proposed DiffKAN-Inpainting inpaints more detailed and realistic reconstructions on the BraTS dataset. The knowledge gained from ablation study provide insights for future research to balance performance with computing cost.
AB - Brain tumors delay the standard preprocessing workflow for further examination. Brain inpainting offers a viable, although difficult, solution for tumor tissue processing, which is necessary to improve the precision of the diagnosis and treatment. Most conventional U-Net-based generative models, however, often face challenges in capturing the complex, nonlinear latent representations inherent in brain imaging. In order to accomplish high-quality healthy brain tissue reconstruction, this work proposes DiffKAN-Inpainting, an innovative method that blends diffusion models with the Kolmogorov-Arnold Networks architecture. During the denoising process, we introduce the RePaint method and tumor information to generate images with a higher fidelity and smoother margin. Both qualitative and quantitative results demonstrate that as compared to the state-of-the-art methods, our proposed DiffKAN-Inpainting inpaints more detailed and realistic reconstructions on the BraTS dataset. The knowledge gained from ablation study provide insights for future research to balance performance with computing cost.
KW - Brain tumor inpainting
KW - Diffusion model
KW - KAN
KW - MRI
UR - https://ieeexplore.ieee.org/document/10980990
UR - http://www.scopus.com/inward/record.url?scp=105005827152&partnerID=8YFLogxK
U2 - 10.1109/ISBI60581.2025.10980990
DO - 10.1109/ISBI60581.2025.10980990
M3 - Conference publication
T3 - Proceedings - International Symposium on Biomedical Imaging
BT - 2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI)
PB - IEEE
ER -