DiffKAN-Inpainting: KAN-Based Diffusion Model for Brain Tumor Inpainting

Tianli Tao, Ziyang Wang, Han Zhang, Theodoros N. Arvanitis, Le Zhang

Research output: Chapter in Book/Published conference outputConference publication

2 Citations (Scopus)

Abstract

Brain tumors delay the standard preprocessing workflow for further examination. Brain inpainting offers a viable, although difficult, solution for tumor tissue processing, which is necessary to improve the precision of the diagnosis and treatment. Most conventional U-Net-based generative models, however, often face challenges in capturing the complex, nonlinear latent representations inherent in brain imaging. In order to accomplish high-quality healthy brain tissue reconstruction, this work proposes DiffKAN-Inpainting, an innovative method that blends diffusion models with the Kolmogorov-Arnold Networks architecture. During the denoising process, we introduce the RePaint method and tumor information to generate images with a higher fidelity and smoother margin. Both qualitative and quantitative results demonstrate that as compared to the state-of-the-art methods, our proposed DiffKAN-Inpainting inpaints more detailed and realistic reconstructions on the BraTS dataset. The knowledge gained from ablation study provide insights for future research to balance performance with computing cost.
Original languageEnglish
Title of host publication2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI)
PublisherIEEE
Number of pages4
ISBN (Electronic)9798331520526
DOIs
Publication statusPublished - 12 May 2025

Publication series

NameProceedings - International Symposium on Biomedical Imaging
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Keywords

  • Brain tumor inpainting
  • Diffusion model
  • KAN
  • MRI

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