Abstract
Brain tumors delay the standard preprocessing workflow for further examination. Brain inpainting offers a viable, although difficult, solution for tumor tissue processing, which is necessary to improve the precision of the diagnosis and treatment. Most conventional U-Net-based generative models, however, often face challenges in capturing the complex, nonlinear latent representations inherent in brain imaging. In order to accomplish high-quality healthy brain tissue reconstruction, this work proposes DiffKAN-Inpainting, an innovative method that blends diffusion models with the Kolmogorov-Arnold Networks architecture. During the denoising process, we introduce the RePaint method and tumor information to generate images with a higher fidelity and smoother margin. Both qualitative and quantitative results demonstrate that as compared to the state-of-the-art methods, our proposed DiffKAN-Inpainting inpaints more detailed and realistic reconstructions on the BraTS dataset. The knowledge gained from ablation study provide insights for future research to balance performance with computing cost.
| Original language | English |
|---|---|
| Title of host publication | 2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI) |
| Publisher | IEEE |
| Number of pages | 4 |
| ISBN (Electronic) | 9798331520526 |
| DOIs | |
| Publication status | Published - 12 May 2025 |
Publication series
| Name | Proceedings - International Symposium on Biomedical Imaging |
|---|---|
| ISSN (Print) | 1945-7928 |
| ISSN (Electronic) | 1945-8452 |
Funding
The work has been partially funded by HDR UK and EU Horizon INSAFEDARE Project - Grant Agreement number: 101095661. This work is also partially supported by the STI 2030-Major Projects (No. 2022ZD0209000), National Natural Science Foundation of China (No. 62203355), Shanghai Pilot Program for Basic Research - Chinese Academy of Science, Shanghai Branch (No. JCYJ-SHFY-2022-014), Shenzhen Science and Technology Program (No. KCXFZ20211020163408012), and Shanghai Pujiang Program (No. 21PJ1421400).
Keywords
- Brain tumor inpainting
- Diffusion model
- KAN
- MRI
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