Distribution ratios of lipase-catalyzed reaction products in ionic liquid supercritical CO2 systems: Resolution of 2-octanol enantiomers

R. Bogel-Łukasik, V. Najdanovic-Visak, S. Barreiros, M.N. Da Ponte

Research output: Contribution to journalArticlepeer-review

Abstract

This paper presents vapor−liquid equilibrium (VLE) data for systems containing high-pressure CO2, an ionic liquid, and products of an enzymatic reaction between succinic anhydride and (R,S)-2-octanol in the presence of a lipase. VLE experiments were used to calculate partition coefficients of reaction products between the ionic liquid-rich phase and the CO2-rich phase. Experiments of extraction with CO2 from an ionic liquid of (S)-2-octanol in conditions similar to those of the postreaction mixture were also carried out. The extraction at 11 MPa and 35 °C allows one to recover completely the unreacted enantiomer of 2-octanol with very high enantiomeric excess (98.42%).
Original languageEnglish
Pages (from-to)4473-4480
JournalIndustrial and Engineering Chemistry Research
Volume47
Issue number13
DOIs
Publication statusPublished - 5 Jun 2008

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