Diverse Profiles of Anxiety Related Disorders in Fragile X, Cornelia de Lange and Rubinstein–Taybi Syndromes

Hayley Crawford, Jane Waite, Chris Oliver

Research output: Contribution to journalArticle

Abstract

Anxiety disorders are heightened in specific genetic syndromes in comparison to intellectual disability of heterogeneous aetiology. In this study, we described and contrasted anxiety symptomatology in fragile X (FXS), Cornelia de Lange (CdLS) and Rubinstein–Taybi syndromes (RTS), and compared the symptomatology to normative data for typically-developing children and children diagnosed with an anxiety disorder. Scores did not differ between children diagnosed with an anxiety disorder and (a) participants with FXS on social phobia, panic/agoraphobia, physical injury fears, and obsessive–compulsive subscales (b) participants with CdLS on separation anxiety, generalized anxiety, panic/agoraphobia, physical injury fears and obsessive–compulsive subscales, and (c) participants with RTS on panic/agoraphobia and obsessive–compulsive subscales. The results highlight divergent profiles of anxiety symptomatology between these groups.
LanguageEnglish
Pages3728-3740
JournalJournal of Autism and Developmental Disorders
Volume47
Issue number12
Early online date31 Jan 2017
DOIs
Publication statusPublished - 1 Dec 2017

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Rubinstein-Taybi Syndrome
Agoraphobia
Panic
Anxiety Disorders
Anxiety
Fear
Separation Anxiety
Wounds and Injuries
Intellectual Disability

Bibliographical note

© The Author(s) 2017. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Cite this

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Diverse Profiles of Anxiety Related Disorders in Fragile X, Cornelia de Lange and Rubinstein–Taybi Syndromes. / Crawford, Hayley; Waite, Jane; Oliver, Chris .

In: Journal of Autism and Developmental Disorders, Vol. 47, No. 12, 01.12.2017, p. 3728-3740.

Research output: Contribution to journalArticle

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