Does transient increase in axial length during accommodation attenuate with age?

Deborah S. Laughton, Amy L. Sheppard, Edward A.H. Mallen, Scott Read, Leon N. Davies*

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Background: The aim was to profile transient accommodative axial length (AXL) changes from early adulthood to advanced presbyopia and to determine whether any differences exist between the responses of myopic and emmetropic individuals.
Methods: Ocular biometry was measured by the LenStar biometer (Haag-Streit, Switzerland) in response to 0.00, 3.00 and 4.50 D accommodative stimuli in 35 emmetropes and 37 myopes, aged 18 to 60 years. All results were corrected to reduce errors arising from the increase in crystalline lens thickness with accommodation. Accommodative responses were measured sequentially by the WAM 5500 Auto Ref/Keratometer (Grand Seiko, Japan).
Results: AXL increased significantly with accommodation (p<0.001), with a mean corrected AXL elongation of 2 ± 18 µm and 8 ± 16 µm observed at 3.00 D and 4.50 D, respectively. The magnitude of accommodative AXL change was not dependent on refractive error classification (p=0.959), however a significant reduction in the magnitude and variance of AXL change was evident after 43-44 years of age (p<0.002).
Conclusion: The negative association between transient AXL elongation and age, in combination with reduced variance of data after age 43-44 years, is consistent with a significant increase in posterior ocular rigidity, which may be influential in the development of presbyopia.
Original languageEnglish
Pages (from-to)676-682
JournalClinical and Experimental Optometry
Volume100
Issue number6
Early online date12 Mar 2017
DOIs
Publication statusPublished - 1 Nov 2017

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Presbyopia
Biometry
Crystalline Lens
Refractive Errors
Switzerland
Japan

Bibliographical note

© 2017 The Authors. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

Keywords

  • accommodation
  • axial length
  • biometry
  • crystalline lens
  • presbyopia

Cite this

Laughton, Deborah S. ; Sheppard, Amy L. ; Mallen, Edward A.H. ; Read, Scott ; Davies, Leon N. / Does transient increase in axial length during accommodation attenuate with age?. In: Clinical and Experimental Optometry. 2017 ; Vol. 100, No. 6. pp. 676-682.
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Does transient increase in axial length during accommodation attenuate with age? / Laughton, Deborah S.; Sheppard, Amy L.; Mallen, Edward A.H.; Read, Scott; Davies, Leon N.

In: Clinical and Experimental Optometry, Vol. 100, No. 6, 01.11.2017, p. 676-682.

Research output: Contribution to journalArticle

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AU - Davies, Leon N.

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N2 - Background: The aim was to profile transient accommodative axial length (AXL) changes from early adulthood to advanced presbyopia and to determine whether any differences exist between the responses of myopic and emmetropic individuals. Methods: Ocular biometry was measured by the LenStar biometer (Haag-Streit, Switzerland) in response to 0.00, 3.00 and 4.50 D accommodative stimuli in 35 emmetropes and 37 myopes, aged 18 to 60 years. All results were corrected to reduce errors arising from the increase in crystalline lens thickness with accommodation. Accommodative responses were measured sequentially by the WAM 5500 Auto Ref/Keratometer (Grand Seiko, Japan). Results: AXL increased significantly with accommodation (p<0.001), with a mean corrected AXL elongation of 2 ± 18 µm and 8 ± 16 µm observed at 3.00 D and 4.50 D, respectively. The magnitude of accommodative AXL change was not dependent on refractive error classification (p=0.959), however a significant reduction in the magnitude and variance of AXL change was evident after 43-44 years of age (p<0.002). Conclusion: The negative association between transient AXL elongation and age, in combination with reduced variance of data after age 43-44 years, is consistent with a significant increase in posterior ocular rigidity, which may be influential in the development of presbyopia.

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