Effect of anisotropy on elastic moduli measured by nanoindentation in human tibial cortical bone

J.G. Swadener, Jae-Young Rho, G.M. Pharr

Research output: Contribution to journalArticle

Abstract

Many biological materials are known to be anisotropic. In particular, microstructural components of biological materials may grow in a preferred direction, giving rise to anisotropy in the microstructure. Nanoindentation has been shown to be an effective technique for determining the mechanical properties of microstructures as small as a few microns. However, the effects of anisotropy on the properties measured by nanoindentation have not been fully addressed. This study presents a method to account for the effects of anisotropy on elastic properties measured by nanoindentation. This method is used to correlate elastic properties determined from earlier nanoindentation experiments and from earlier ultrasonic velocity measurements in human tibial cortical bone. Also presented is a procedure to determine anisotropic elastic moduli from indentation measurements in multiple directions.
Original languageEnglish
Pages (from-to)108-112
Number of pages5
JournalJournal of Biomedical Materials Research: Part A
Volume57
Issue number1
Early online date14 Jun 2001
DOIs
Publication statusPublished - Oct 2001

Fingerprint

Nanoindentation
Bone
Anisotropy
Elastic moduli
Biological materials
Ultrasonic velocity measurement
Microstructure
Indentation
Mechanical properties
Experiments
Direction compound

Keywords

  • anisotropy
  • cortical bone
  • elastic modulus
  • nanoindentation
  • ultrasonic velocity

Cite this

@article{f87b88abf7864ef6bae0d8c771a8cb13,
title = "Effect of anisotropy on elastic moduli measured by nanoindentation in human tibial cortical bone",
abstract = "Many biological materials are known to be anisotropic. In particular, microstructural components of biological materials may grow in a preferred direction, giving rise to anisotropy in the microstructure. Nanoindentation has been shown to be an effective technique for determining the mechanical properties of microstructures as small as a few microns. However, the effects of anisotropy on the properties measured by nanoindentation have not been fully addressed. This study presents a method to account for the effects of anisotropy on elastic properties measured by nanoindentation. This method is used to correlate elastic properties determined from earlier nanoindentation experiments and from earlier ultrasonic velocity measurements in human tibial cortical bone. Also presented is a procedure to determine anisotropic elastic moduli from indentation measurements in multiple directions.",
keywords = "anisotropy, cortical bone, elastic modulus, nanoindentation, ultrasonic velocity",
author = "J.G. Swadener and Jae-Young Rho and G.M. Pharr",
note = "Copyright 2007 Elsevier B.V., All rights reserved.",
year = "2001",
month = "10",
doi = "10.1002/1097-4636(200110)57:1<108::AID-JBM1148>3.0.CO;2-6",
language = "English",
volume = "57",
pages = "108--112",
journal = "Journal of Biomedical Materials Research: Part A",
issn = "1549-3296",
publisher = "John Wiley and Sons Inc.",
number = "1",

}

Effect of anisotropy on elastic moduli measured by nanoindentation in human tibial cortical bone. / Swadener, J.G.; Rho, Jae-Young; Pharr, G.M.

In: Journal of Biomedical Materials Research: Part A, Vol. 57, No. 1, 10.2001, p. 108-112.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Effect of anisotropy on elastic moduli measured by nanoindentation in human tibial cortical bone

AU - Swadener, J.G.

AU - Rho, Jae-Young

AU - Pharr, G.M.

N1 - Copyright 2007 Elsevier B.V., All rights reserved.

PY - 2001/10

Y1 - 2001/10

N2 - Many biological materials are known to be anisotropic. In particular, microstructural components of biological materials may grow in a preferred direction, giving rise to anisotropy in the microstructure. Nanoindentation has been shown to be an effective technique for determining the mechanical properties of microstructures as small as a few microns. However, the effects of anisotropy on the properties measured by nanoindentation have not been fully addressed. This study presents a method to account for the effects of anisotropy on elastic properties measured by nanoindentation. This method is used to correlate elastic properties determined from earlier nanoindentation experiments and from earlier ultrasonic velocity measurements in human tibial cortical bone. Also presented is a procedure to determine anisotropic elastic moduli from indentation measurements in multiple directions.

AB - Many biological materials are known to be anisotropic. In particular, microstructural components of biological materials may grow in a preferred direction, giving rise to anisotropy in the microstructure. Nanoindentation has been shown to be an effective technique for determining the mechanical properties of microstructures as small as a few microns. However, the effects of anisotropy on the properties measured by nanoindentation have not been fully addressed. This study presents a method to account for the effects of anisotropy on elastic properties measured by nanoindentation. This method is used to correlate elastic properties determined from earlier nanoindentation experiments and from earlier ultrasonic velocity measurements in human tibial cortical bone. Also presented is a procedure to determine anisotropic elastic moduli from indentation measurements in multiple directions.

KW - anisotropy

KW - cortical bone

KW - elastic modulus

KW - nanoindentation

KW - ultrasonic velocity

UR - http://www.scopus.com/inward/record.url?scp=0034743338&partnerID=8YFLogxK

UR - http://onlinelibrary.wiley.com/doi/10.1002/1097-4636(200110)57:1<108::AID-JBM1148>3.0.CO;2-6/abstract

U2 - 10.1002/1097-4636(200110)57:1<108::AID-JBM1148>3.0.CO;2-6

DO - 10.1002/1097-4636(200110)57:1<108::AID-JBM1148>3.0.CO;2-6

M3 - Article

AN - SCOPUS:0034743338

VL - 57

SP - 108

EP - 112

JO - Journal of Biomedical Materials Research: Part A

JF - Journal of Biomedical Materials Research: Part A

SN - 1549-3296

IS - 1

ER -