Extended wear contact lenses

B.J. Tighe*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The chapter shows how the successful design of polymers for contact lens applications depends on the need to provide a balance of properties appropriate to the ocular environment. The principal relevant aspects of the anterior eye are tear film, eyelid and cornea, which govern the requirements for surface properties, modulus and oxygen permeability, respectively. In the case of extended (overnight) wear, oxygen permeability is the most critical because of the reduced availability of oxygen to the avascular cornea. The relationship between permeability requirements and the developing view of the needs of the cornea, in terms of oxygen consumption, are discussed and the particular roles of fluorine and silicon in the design of successful polymers described. The evolution of polymer design is taken as a background for the consideration of the current generation of silicone hydrogels, which have proved to be the most successful family of materials for this demanding application. 2010 Woodhead Publishing Limited All rights reserved.

Original languageEnglish
Title of host publicationBiomaterials and regenerative medicine in ophthalmology
EditorsTraian V. Chirila
Place of PublicationCambridge (UK)
PublisherWoodhead
Pages304-336
Number of pages33
ISBN (Print)978-1-84569-443-2
DOIs
Publication statusPublished - 2009

Publication series

NameWoodhead Publishing Series in Biomaterials
PublisherWoodhead Publishing

Fingerprint

Contact lenses
Wear of materials
Oxygen
Polymers
Hydrogels
Fluorine
Silicon
Silicones
Surface properties
Availability

Cite this

Tighe, B. J. (2009). Extended wear contact lenses. In T. V. Chirila (Ed.), Biomaterials and regenerative medicine in ophthalmology (pp. 304-336). (Woodhead Publishing Series in Biomaterials). Cambridge (UK): Woodhead. https://doi.org/10.1533/9781845697433.1.304
Tighe, B.J. / Extended wear contact lenses. Biomaterials and regenerative medicine in ophthalmology. editor / Traian V. Chirila. Cambridge (UK) : Woodhead, 2009. pp. 304-336 (Woodhead Publishing Series in Biomaterials).
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Tighe, BJ 2009, Extended wear contact lenses. in TV Chirila (ed.), Biomaterials and regenerative medicine in ophthalmology. Woodhead Publishing Series in Biomaterials, Woodhead, Cambridge (UK), pp. 304-336. https://doi.org/10.1533/9781845697433.1.304

Extended wear contact lenses. / Tighe, B.J.

Biomaterials and regenerative medicine in ophthalmology. ed. / Traian V. Chirila. Cambridge (UK) : Woodhead, 2009. p. 304-336 (Woodhead Publishing Series in Biomaterials).

Research output: Chapter in Book/Report/Conference proceedingChapter

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AB - The chapter shows how the successful design of polymers for contact lens applications depends on the need to provide a balance of properties appropriate to the ocular environment. The principal relevant aspects of the anterior eye are tear film, eyelid and cornea, which govern the requirements for surface properties, modulus and oxygen permeability, respectively. In the case of extended (overnight) wear, oxygen permeability is the most critical because of the reduced availability of oxygen to the avascular cornea. The relationship between permeability requirements and the developing view of the needs of the cornea, in terms of oxygen consumption, are discussed and the particular roles of fluorine and silicon in the design of successful polymers described. The evolution of polymer design is taken as a background for the consideration of the current generation of silicone hydrogels, which have proved to be the most successful family of materials for this demanding application. 2010 Woodhead Publishing Limited All rights reserved.

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Tighe BJ. Extended wear contact lenses. In Chirila TV, editor, Biomaterials and regenerative medicine in ophthalmology. Cambridge (UK): Woodhead. 2009. p. 304-336. (Woodhead Publishing Series in Biomaterials). https://doi.org/10.1533/9781845697433.1.304