Extended wear contact lenses

B.J. Tighe

doi:10.1533/9781845697433.1.304

Extended wear contact lenses

B.J. Tighe^*

^*Corresponding author for this work

Research output: Chapter in Book/Published conference output › Chapter

12 Citations (Scopus)

Abstract

The chapter shows how the successful design of polymers for contact lens applications depends on the need to provide a balance of properties appropriate to the ocular environment. The principal relevant aspects of the anterior eye are tear film, eyelid and cornea, which govern the requirements for surface properties, modulus and oxygen permeability, respectively. In the case of extended (overnight) wear, oxygen permeability is the most critical because of the reduced availability of oxygen to the avascular cornea. The relationship between permeability requirements and the developing view of the needs of the cornea, in terms of oxygen consumption, are discussed and the particular roles of fluorine and silicon in the design of successful polymers described. The evolution of polymer design is taken as a background for the consideration of the current generation of silicone hydrogels, which have proved to be the most successful family of materials for this demanding application. 2010 Woodhead Publishing Limited All rights reserved.

Original language	English
Title of host publication	Biomaterials and regenerative medicine in ophthalmology
Editors	Traian V. Chirila
Place of Publication	Cambridge (UK)
Publisher	Woodhead
Pages	304-336
Number of pages	33
ISBN (Print)	978-1-84569-443-2
DOIs	https://doi.org/10.1533/9781845697433.1.304
Publication status	Published - 2009

Publication series

Name	Woodhead Publishing Series in Biomaterials
Publisher	Woodhead Publishing

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10.1533/9781845697433.1.304

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title = "Extended wear contact lenses",

abstract = "The chapter shows how the successful design of polymers for contact lens applications depends on the need to provide a balance of properties appropriate to the ocular environment. The principal relevant aspects of the anterior eye are tear film, eyelid and cornea, which govern the requirements for surface properties, modulus and oxygen permeability, respectively. In the case of extended (overnight) wear, oxygen permeability is the most critical because of the reduced availability of oxygen to the avascular cornea. The relationship between permeability requirements and the developing view of the needs of the cornea, in terms of oxygen consumption, are discussed and the particular roles of fluorine and silicon in the design of successful polymers described. The evolution of polymer design is taken as a background for the consideration of the current generation of silicone hydrogels, which have proved to be the most successful family of materials for this demanding application. 2010 Woodhead Publishing Limited All rights reserved.",

author = "B.J. Tighe",

year = "2009",

doi = "10.1533/9781845697433.1.304",

language = "English",

isbn = "978-1-84569-443-2",

series = "Woodhead Publishing Series in Biomaterials",

publisher = "Woodhead",

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editor = "Chirila, \{Traian V.\}",

booktitle = "Biomaterials and regenerative medicine in ophthalmology",

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TY - CHAP

T1 - Extended wear contact lenses

AU - Tighe, B.J.

PY - 2009

Y1 - 2009

N2 - The chapter shows how the successful design of polymers for contact lens applications depends on the need to provide a balance of properties appropriate to the ocular environment. The principal relevant aspects of the anterior eye are tear film, eyelid and cornea, which govern the requirements for surface properties, modulus and oxygen permeability, respectively. In the case of extended (overnight) wear, oxygen permeability is the most critical because of the reduced availability of oxygen to the avascular cornea. The relationship between permeability requirements and the developing view of the needs of the cornea, in terms of oxygen consumption, are discussed and the particular roles of fluorine and silicon in the design of successful polymers described. The evolution of polymer design is taken as a background for the consideration of the current generation of silicone hydrogels, which have proved to be the most successful family of materials for this demanding application. 2010 Woodhead Publishing Limited All rights reserved.

AB - The chapter shows how the successful design of polymers for contact lens applications depends on the need to provide a balance of properties appropriate to the ocular environment. The principal relevant aspects of the anterior eye are tear film, eyelid and cornea, which govern the requirements for surface properties, modulus and oxygen permeability, respectively. In the case of extended (overnight) wear, oxygen permeability is the most critical because of the reduced availability of oxygen to the avascular cornea. The relationship between permeability requirements and the developing view of the needs of the cornea, in terms of oxygen consumption, are discussed and the particular roles of fluorine and silicon in the design of successful polymers described. The evolution of polymer design is taken as a background for the consideration of the current generation of silicone hydrogels, which have proved to be the most successful family of materials for this demanding application. 2010 Woodhead Publishing Limited All rights reserved.

UR - https://www.scopus.com/pages/publications/84878124611

U2 - 10.1533/9781845697433.1.304

DO - 10.1533/9781845697433.1.304

M3 - Chapter

AN - SCOPUS:84878124611

SN - 978-1-84569-443-2

T3 - Woodhead Publishing Series in Biomaterials

SP - 304

EP - 336

BT - Biomaterials and regenerative medicine in ophthalmology

A2 - Chirila, Traian V.

PB - Woodhead

CY - Cambridge (UK)

ER -

Extended wear contact lenses

Abstract

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Physicochemical properties of hydrogels for use in ophthalmology

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