Small-molecule crystallography plays a significant part in the design of drugs, especially those which bind tightly to receptors. In some cases, the macromolecular target structure is unknown. In others, structural properties of the drug are required to regulate solubility or polymorphism. Several examples are given.
|Number of pages||12|
|Publication status||Published - 1 Jan 2005|
- Drug design
- Hydrogen bonding
- Small-molecule crystallography