Graphene based nanomaterials (GBN) have been recently applied in a broad range of science and technology fields such as nanobiomedicine, electronics, energy storage and power generation exploiting their unique electronic structure, physical properties, and opportunities for modifying their surface using covalent and non-covalent interactions. In the present review we systematised the origins of GBN functionalisation using organic and inorganic molecules, polymers, biomolecules, and anticancer drugs. We show that varying the procedure of GBN functionalisation allows to obtain nanomaterials with desired properties that can be applied to the development of materials with enhanced physicochemical properties, nanoplatforms for drug delivery, nanobiosensors for detection of various biomolecules, as well as nanomaterials for bioimaging and diagnostics. The review can be useful for experts in the fields of material science and nanobiomedicine.
Bibliographical note© 2021, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/
The work was supported by the Council on Grants of the President of the Russian Federation for State Support of Young Scientists (MD-741.2020.7). The research of Abdelsattar Osama Elemam Abdelhalim is funded by the scholarship EGY-6218/17 under the Joint Executive Program between the Arab Republic of Egypt and the Russian Federation. The equipment of the following Resource Centres of the Research Park of Saint Petersburg State University was used: Resource Centre “GeoModel”, the Centre for Diagnostics of Functional Materials for Medicine, Pharmacology and Nanoelectronics, Interdisciplinary Resource Centre for Nanotechnology, Magnetic Resonance Research Centre, Centre for Physical Methods of Surface Investigation, Centre for Chemical Analysis and Materials Research, Thermogravimetric and Calorimetric Research Centre.
- Drug delivery
- Graphene oxide