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Going beyond glycaemic control to address insulin resistance

  • Karolinska Institutet

Research output: Contribution to journalArticlepeer-review

Abstract

Insulin resistance underpins the development of type 2 diabetes and is the centre of the cluster of cardiovascular risk factors termed the insulin resistance syndrome. Increased cardiovascular risk is established in the prediabetic phase whereas the risk of microvascular complications is associated with overt diabetes. The success of monotherapy is usually partial and/or temporary. A new class of agents, the thiazoidinediones, addresses insulin resistance, targeting peroxisome proliferator-activated receptor gamma. These agents have considerable clinical potential.

Original languageEnglish
JournalBritish Journal of Cardiology
Volume8
Issue numberSUPPL. 4
Publication statusPublished - 1 Dec 2001

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Cardiovascular risk
  • Combination therapy
  • Glycaemic control
  • Insulin resistance
  • Thiazolidinediones
  • Type 2 diabetes

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