GPCRTree: online hierarchical classification of GPCR function

Matthew N. Davies, Andrew Secker, Mark Halling-Brown, David S. Moss, Alex A. Freitas, Jon Timmis, Edward Clark, Darren R Flower

Research output: Contribution to journalArticle

Abstract

G protein-coupled receptors (GPCRs) play important physiological roles transducing extracellular signals into intracellular responses. Approximately 50% of all marketed drugs target a GPCR. There remains considerable interest in effectively predicting the function of a GPCR from its primary sequence.
Original languageEnglish
Article number67
Pages (from-to)67
JournalBMC Research Notes
Volume1
DOIs
Publication statusPublished - 21 Aug 2008

Bibliographical note

© 2008 Davies et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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    Davies, M. N., Secker, A., Halling-Brown, M., Moss, D. S., Freitas, A. A., Timmis, J., Clark, E., & Flower, D. R. (2008). GPCRTree: online hierarchical classification of GPCR function. BMC Research Notes, 1, 67. [67]. https://doi.org/10.1186/1756-0500-1-67