Graphene-based silica fiber-optic sensors, with high sensitivity, fast response, and low cost, have shown great promise for gas sensing applications. In this letter, by covering a monolayer of p-doped graphene on a D-shaped microstructured polymer fiber Bragg grating (FBG), we propose and demonstrate a novel biochemical probe sensor, the graphene-based D-shaped polymer FBG (GDPFBG). Due to the graphene-based surface evanescent field enhancement, this sensor shows high sensitivity to detect surrounding biochemical parameters. By monitoring the Bragg peak locations of the GDPFBG online, human erythrocyte (red blood cell) solutions with different cellular concentrations ranging from 0 to 104 ppm were detected precisely, with the maximum resolution of sub-ppm. Such a sensor is structurally compact, is clinically acceptable, and provides good recoverability, offering a state-of-the-art polymer-fiber-based sensing platform for highly sensitive in situ and in vivo cell detection applications.
Bibliographical noteFunding: National Natural Science Foundation of China under (61290312, 61107072, 61107073, and 61475032); Program for Changjiang Scholars and Innovative Research Team in Universities of China; 111 Project through the Ministry of Education, China; People Programme (Marie Curie Actions) EC 7FP (FP7/2007-2013) REA Project under (608382).
- optical fiber sensors
- p-doped graphene
- erythrocyte sensor
- fiber Bragg gratings