Human corneal stromal lamellar organisation: A polarised light study in pseudophakic eyes

G. P. Misson; B. H. Timmerman; P. J. Bryanston-Cross

doi:10.1080/09500340701467801

Human corneal stromal lamellar organisation: A polarised light study in pseudophakic eyes

G. P. Misson^*, B. H. Timmerman, P. J. Bryanston-Cross

^*Corresponding author for this work

Optometry

Research output: Contribution to journal › Article › peer-review

Abstract

A novel qualitative method is presented for determining the macroscopic distribution of collagen lamellae within the central human cornea in vivo. A modified digital photo slit-lamp camera adapted for use with circular polarised light is used. 19 eyes of 10 pseudophakic subjects (with prosthetic intraocular lens implants) are involved in the experiment. Confocal elliptic/hyperbolic populations of collagen fibrils in central and intermediate corneal zones are identified in all eyes with a superotemporal-inferonasal preferred orientation. Approximate mirror symmetry is found to exist between pairs of eyes. The results demonstrate capability for detail not previously reported. The identified distribution of central collagen is consistent with the reported birefringent properties of the central cornea and is compatible with X-ray scatter findings.

Original language	English
Pages (from-to)	625-637
Number of pages	13
Journal	Journal of Modern Optics
Volume	55
Issue number	4-5
DOIs	https://doi.org/10.1080/09500340701467801
Publication status	Published - 1 Feb 2008

Keywords

Circular polarised light
Collagen
Cornea
Ophthalmology
Stroma
Structure

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10.1080/09500340701467801

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title = "Human corneal stromal lamellar organisation: A polarised light study in pseudophakic eyes",

abstract = "A novel qualitative method is presented for determining the macroscopic distribution of collagen lamellae within the central human cornea in vivo. A modified digital photo slit-lamp camera adapted for use with circular polarised light is used. 19 eyes of 10 pseudophakic subjects (with prosthetic intraocular lens implants) are involved in the experiment. Confocal elliptic/hyperbolic populations of collagen fibrils in central and intermediate corneal zones are identified in all eyes with a superotemporal-inferonasal preferred orientation. Approximate mirror symmetry is found to exist between pairs of eyes. The results demonstrate capability for detail not previously reported. The identified distribution of central collagen is consistent with the reported birefringent properties of the central cornea and is compatible with X-ray scatter findings.",

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T1 - Human corneal stromal lamellar organisation

T2 - A polarised light study in pseudophakic eyes

AU - Misson, G. P.

AU - Timmerman, B. H.

AU - Bryanston-Cross, P. J.

PY - 2008/2/1

Y1 - 2008/2/1

N2 - A novel qualitative method is presented for determining the macroscopic distribution of collagen lamellae within the central human cornea in vivo. A modified digital photo slit-lamp camera adapted for use with circular polarised light is used. 19 eyes of 10 pseudophakic subjects (with prosthetic intraocular lens implants) are involved in the experiment. Confocal elliptic/hyperbolic populations of collagen fibrils in central and intermediate corneal zones are identified in all eyes with a superotemporal-inferonasal preferred orientation. Approximate mirror symmetry is found to exist between pairs of eyes. The results demonstrate capability for detail not previously reported. The identified distribution of central collagen is consistent with the reported birefringent properties of the central cornea and is compatible with X-ray scatter findings.

AB - A novel qualitative method is presented for determining the macroscopic distribution of collagen lamellae within the central human cornea in vivo. A modified digital photo slit-lamp camera adapted for use with circular polarised light is used. 19 eyes of 10 pseudophakic subjects (with prosthetic intraocular lens implants) are involved in the experiment. Confocal elliptic/hyperbolic populations of collagen fibrils in central and intermediate corneal zones are identified in all eyes with a superotemporal-inferonasal preferred orientation. Approximate mirror symmetry is found to exist between pairs of eyes. The results demonstrate capability for detail not previously reported. The identified distribution of central collagen is consistent with the reported birefringent properties of the central cornea and is compatible with X-ray scatter findings.

KW - Circular polarised light

KW - Collagen

KW - Cornea

KW - Ophthalmology

KW - Stroma

KW - Structure

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ER -

Human corneal stromal lamellar organisation: A polarised light study in pseudophakic eyes

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