A novel qualitative method is presented for determining the macroscopic distribution of collagen lamellae within the central human cornea in vivo. A modified digital photo slit-lamp camera adapted for use with circular polarised light is used. 19 eyes of 10 pseudophakic subjects (with prosthetic intraocular lens implants) are involved in the experiment. Confocal elliptic/hyperbolic populations of collagen fibrils in central and intermediate corneal zones are identified in all eyes with a superotemporal-inferonasal preferred orientation. Approximate mirror symmetry is found to exist between pairs of eyes. The results demonstrate capability for detail not previously reported. The identified distribution of central collagen is consistent with the reported birefringent properties of the central cornea and is compatible with X-ray scatter findings.
|Number of pages||13|
|Journal||Journal of Modern Optics|
|Publication status||Published - 1 Feb 2008|
- Circular polarised light