Abstract
Simple stirring of a mixture of the alkynyl(phenyl)iodonium salts 1 with 2-aminopyrimidine 2 in chloroform under reflux for two hours in the presence of K2CO3 gave, after workup, the 2-substituted imidazo[1,2-]pyrimidines 3 in moderate to good yields. A possible mechanism for the formation of 3 involves the intramolecular cyclization of the intermediate alkylidenecarbene 6.
| Original language | English |
|---|---|
| Pages (from-to) | 909-911 |
| Number of pages | 3 |
| Journal | Journal of Heterocyclic Chemistry |
| Volume | 40 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Sept 2003 |
Keywords
- alkynyl(phenyl)iodonium salts 1
- 2-aminopyrimidine 2 in chloroform
- reflux
- K2CO3
- 2-substituted imidazo[1
- 2-]pyrimidines 3
- intramolecular cyclization
- intermediate alkylidenecarbene 6
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