Identifying spatially overlapping local cortical networks with MEG

Keith Kawabata Duncan, Avgis Hadjipapas, Sheng Li, Zoe Kourtzi, Andy Bagshaw, Gareth Barnes*

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Recent modelling studies (Hadjipapas et al. [2009]: Neuroimage 44:1290-1303) have shown that it may be possible to distinguish between different neuronal populations on the basis of their macroscopically measured (EEG/MEG) mean field. We set out to test whether the different orientation columns contributing to a signal at a specific cortical location could be identified based on the measured MEG signal. We used 1.5deg square, static, obliquely oriented grating stimuli to generate sustained gamma oscillations in a focal region of primary visual cortex. We then used multivariate classifier methods to predict the orientation (left or right oblique) of the stimuli based purely on the time-series data from this one location. Both the single trial evoked response (0-300 ms) and induced post-transient power spectra (300-2,300 ms, 20-70 Hz band) due to the different stimuli were classifiable significantly above chance in 11/12 and 10/12 datasets respectively. Interestingly, stimulus-specific information is preserved in the sustained part of the gamma oscillation, long after perception has occurred and all neuronal transients have decayed. Importantly, the classification of this induced oscillation was still possible even when the power spectra were rank-transformed showing that the different underlying networks give rise to different characteristic temporal signatures.

Original languageEnglish
Pages (from-to)1003-1016
Number of pages14
JournalHuman Brain Mapping
Volume31
Issue number7
Early online date8 Dec 2009
DOIs
Publication statusPublished - Jul 2010

Bibliographical note

© 2010 Wiley-Liss, Inc., A Wiley Company
Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.

Keywords

  • beamformer
  • classifier
  • gamma
  • grating
  • mean field
  • MEG
  • orientation

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    Duncan, K. K., Hadjipapas, A., Li, S., Kourtzi, Z., Bagshaw, A., & Barnes, G. (2010). Identifying spatially overlapping local cortical networks with MEG. Human Brain Mapping, 31(7), 1003-1016. https://doi.org/10.1002/hbm.20912