DSM-5 Autism Spectrum Disorder: in search of essential behaviours for diagnosis

Sarah J. Carrington, Rachel G. Kent, Jarymke Maljaars, Ann Le Couteur, Judith Gould, Lorna Wing, Ilse Noens, Ina van Berckelaer-Onnes, Susan R. Leekam

Research output: Contribution to journalArticle

Abstract

The objective of this study was to identify a set of 'essential' behaviours sufficient for diagnosis of DSM-5 Autism Spectrum Disorder (ASD). Highly discriminating, 'essential' behaviours were identified from the published DSM-5 algorithm developed for the Diagnostic Interview for Social and Communication Disorders (DISCO). Study 1 identified a reduced item set (48 items) with good predictive validity (as measured using receiver operating characteristic curves) that represented all symptom sub-domains described in the DSM-5 ASD criteria but lacked sensitivity for individuals with higher ability. An adjusted essential item set (54 items; Study 2) had good sensitivity when applied to individuals with higher ability and performance was comparable to the published full DISCO DSM-5 algorithm. Investigation at the item level revealed that the most highly discriminating items predominantly measured social-communication behaviours. This work represents a first attempt to derive a reduced set of behaviours for DSM-5 directly from an existing standardised ASD developmental history interview and has implications for the use of DSM-5 criteria for clinical and research practice.

LanguageEnglish
Pages701-715
Number of pages15
JournalResearch in autism spectrum disorders
Volume8
Issue number6
Early online date4 Apr 2014
DOIs
Publication statusPublished - Jun 2014

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Aptitude
Interviews
ROC Curve
Communication
Autism Spectrum Disorder
Research
Social Communication Disorder

Bibliographical note

© 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/)

Keywords

  • abbreviaved
  • autism spectrum disorder
  • diagnosis
  • DISCO
  • DSM-5

Cite this

Carrington, Sarah J. ; Kent, Rachel G. ; Maljaars, Jarymke ; Le Couteur, Ann ; Gould, Judith ; Wing, Lorna ; Noens, Ilse ; van Berckelaer-Onnes, Ina ; Leekam, Susan R. / DSM-5 Autism Spectrum Disorder : in search of essential behaviours for diagnosis. In: Research in autism spectrum disorders. 2014 ; Vol. 8, No. 6. pp. 701-715.
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Carrington, SJ, Kent, RG, Maljaars, J, Le Couteur, A, Gould, J, Wing, L, Noens, I, van Berckelaer-Onnes, I & Leekam, SR 2014, 'DSM-5 Autism Spectrum Disorder: in search of essential behaviours for diagnosis' Research in autism spectrum disorders, vol. 8, no. 6, pp. 701-715. https://doi.org/10.1016/j.rasd.2014.03.017

DSM-5 Autism Spectrum Disorder : in search of essential behaviours for diagnosis. / Carrington, Sarah J.; Kent, Rachel G.; Maljaars, Jarymke; Le Couteur, Ann; Gould, Judith; Wing, Lorna; Noens, Ilse; van Berckelaer-Onnes, Ina; Leekam, Susan R.

In: Research in autism spectrum disorders, Vol. 8, No. 6, 06.2014, p. 701-715.

Research output: Contribution to journalArticle

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