Increased global transcription activity as a mechanism of replication stress in cancer

Keyphrases

• DNA Damage 100%
• In Cancer 100%
• Global Transcription 100%
• Replication Stress 100%
• Oncogene-induced Replication Stress 100%
• Transcription Activity 100%
• RNA Synthesis 66%
• Oncogene 66%
• Genomic Instability 66%
• Replication Fork 66%
• TATA-binding Protein 66%
• General Transcription Factor 66%
• Overexpression 33%
• Overexpressing 33%
• Disease-associated 33%
• Molecular Mechanism 33%
• Senescence 33%
• Molecular Link 33%
• R-loops 33%
• Transcription Machinery 33%
• Oncogene Activation 33%
• Hyperproliferation 33%

Biochemistry, Genetics and Molecular Biology

• Oncogene 100%
• Transcription 100%
• DNA Damage 50%
• Genome Instability 33%
• RNA Synthesis 33%
• General Transcription Factor 33%
• TATA-binding Protein 33%
• Upregulation 16%
• R-Loop 16%