Induction of protein degradation in skeletal muscle by a phorbol ester involves upregulation of the ubiquitin-proteasome proteolytic pathway

Keyphrases

• Skeletal muscle 100%
• Protein Degradation 100%
• Proteolytic Cascade 100%
• Ubiquitin-proteasome System 100%
• Acetate 100%
• Phorbol Ester 100%
• Protein Kinase 42%
• Nuclear factor-B 28%
• Total Protein 28%
• Incubation Time 28%
• Disease States 14%
• Muscle Atrophy 14%
• Nuclear Accumulation 14%
• Myosin 14%
• Muscle Cells 14%
• Deubiquitinating Enzyme 14%
• 20S Proteasome 14%
• Myotubes 14%
• Dose-response Curve 14%
• Maximal Effect 14%
• Proteasome Subunits 14%
• Lactacystin 14%
• Protease Inhibitors 14%
• Transcription Factor 14%
• Functional Activity 14%
• Incomplete Knowledge 14%
• Myofibrillar Protein 14%
• NF-B 14%
• Inhibitory Proteins 14%
• Co-incubation 14%
• Induced Activation 14%
• Calphostin C 14%
• Cellular Mechanisms 14%
• Resveratrol 14%
• Induced Degradation 14%
• Cellular Content 14%
• Protein Kinase C Inhibitor 14%

Biochemistry, Genetics and Molecular Biology

• Skeletal Muscle 100%
• Protein Catabolism 100%
• Proteasome 100%
• Ubiquitin 100%
• Upregulation 100%
• calcium activated,phospholipid dependent protein kinase 57%
• Incubation Time 28%
• Complement Factor B 28%
• Ubiquitin-Conjugating Enzyme 14%
• Proteasome Inhibitor 14%
• Dose Response 14%
• Transcription Factors 14%
• Calphostin C 14%
• Resveratrol 14%
• Myosin 14%

Pharmacology, Toxicology and Pharmaceutical Science

• Proteasome 100%
• Ubiquitin 100%
• Phorbol Ester 100%
• calcium activated,phospholipid dependent protein kinase 42%
• Incubation Time 28%
• Alternative Complement Pathway C3 C5 Convertase 28%
• Nuclear Factor 28%
• Protein 28%
• Muscle Atrophy 14%
• Muscle Protein 14%
• Ubiquitin Conjugating Enzyme 14%
• Lactacystin 14%
• Transcription Factors 14%
• Proteasome Inhibitor 14%
• Calphostin C 14%
• Resveratrol 14%
• Protein Kinase C Inhibitor 14%
• Diseases 14%