Influence of probe pressure on diffuse reflectance spectra of human skin measured in vivo

Alexey P. Popov, Alexander V. Bykov, Igor V. Meglinski

Research output: Contribution to journalArticle

Abstract

Mechanical pressure superficially applied on the human skin surface by a fiber-optic probe influences the spatial distribution of blood within the cutaneous tissues. Upon gradual load of weight on the probe, a stepwise increase in the skin reflectance spectra is observed. The decrease in the load follows the similar inverse staircase-like tendency. The observed stepwise reflectance spectra changes are due to, respectively, sequential extrusion of blood from the topical cutaneous vascular beds and their filling afterward. The obtained results are confirmed by Monte Carlo modeling. This implies that pressure-induced influence during the human skin diffuse reflectance spectra measurements in vivo should be taken into consideration, in particular, in the rapidly developing area of wearable gadgets for real-time monitoring of various human body parameters.

Original languageEnglish
Article number110504
JournalJournal of Biomedical Optics
Volume22
Issue number11
DOIs
Publication statusPublished - 20 Nov 2017

Bibliographical note

© 2017 SPIE

Keywords

  • cutaneous vascular beds
  • diffuse reflectance spectra
  • human skin
  • probe pressure

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