Abstract
This is the first comprehensive book about the relationship between apoptosis and autoimmune diseases.
It offers a unique up–to–date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies.
It offers a unique up–to–date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies.
| Original language | English |
|---|---|
| Title of host publication | Apoptosis and autoimmunity |
| Subtitle of host publication | from mechanisms to treatments |
| Editors | M. Hermann, J.R. Kalden |
| Place of Publication | Weinheim (DE) |
| Publisher | Wiley |
| Pages | 111-132 |
| Number of pages | 21 |
| ISBN (Print) | 3-527-30442-8, 978-3-527-30442-4 |
| Publication status | Published - 21 Jan 2003 |