Abstract
| Original language | English |
|---|---|
| Title of host publication | Computational pharmaceutics |
| Subtitle of host publication | application of molecular modeling in drug delivery |
| Editors | Defang Ouyang, Sean C. Smith |
| Place of Publication | Chichester (UK) |
| Publisher | Wiley |
| Pages | 1-5 |
| Number of pages | 5 |
| ISBN (Electronic) | 978-1-118-57398-3 |
| ISBN (Print) | 978-1-118-57399-0 |
| DOIs | |
| Publication status | Published - 29 Jun 2015 |
Publication series
| Name | Advances in Pharmaceutical Technolog |
|---|---|
| Publisher | Wiley |
Fingerprint
Cite this
}
Introduction to computational pharmaceutics. / Ouyang, Defang; Smith, Sean C.
Computational pharmaceutics: application of molecular modeling in drug delivery. ed. / Defang Ouyang; Sean C. Smith. Chichester (UK) : Wiley, 2015. p. 1-5 (Advances in Pharmaceutical Technolog).Research output: Chapter in Book/Report/Conference proceeding › Chapter
TY - CHAP
T1 - Introduction to computational pharmaceutics
AU - Ouyang, Defang
AU - Smith, Sean C.
PY - 2015/6/29
Y1 - 2015/6/29
N2 - Computational pharmaceutics has the ability to provide multiscale lenses to pharmaceutical scientists, revealing mechanistic details ranging across the chemical reactions of small drug molecules, proteins, nucleic acids, nanoparticles, and powders with the human body. This chapter provides an introduction to the application of computational modeling techniques to problems relating to pharmaceutics (drug delivery and formulation development) that will be of great relevance for pharmaceutical scientists and computational chemists in both industry and academia. Contributions from leading researchers cover both computational modeling methodologies and various examples where these methods have been applied successfully in this field. Crystal structure prediction (CSP) methods have gained wide attention from pharmaceutical scientists. Polymeric-based micellar vehicles have been widely used in pharmaceutics for the delivery of both hydrophilic and lipophilic drugs. Physiology-based pharmacokinetics plays an important role in pre-clinical drug development and formulation development.
AB - Computational pharmaceutics has the ability to provide multiscale lenses to pharmaceutical scientists, revealing mechanistic details ranging across the chemical reactions of small drug molecules, proteins, nucleic acids, nanoparticles, and powders with the human body. This chapter provides an introduction to the application of computational modeling techniques to problems relating to pharmaceutics (drug delivery and formulation development) that will be of great relevance for pharmaceutical scientists and computational chemists in both industry and academia. Contributions from leading researchers cover both computational modeling methodologies and various examples where these methods have been applied successfully in this field. Crystal structure prediction (CSP) methods have gained wide attention from pharmaceutical scientists. Polymeric-based micellar vehicles have been widely used in pharmaceutics for the delivery of both hydrophilic and lipophilic drugs. Physiology-based pharmacokinetics plays an important role in pre-clinical drug development and formulation development.
U2 - 10.1002/9781118573983.ch1
DO - 10.1002/9781118573983.ch1
M3 - Chapter
SN - 978-1-118-57399-0
T3 - Advances in Pharmaceutical Technolog
SP - 1
EP - 5
BT - Computational pharmaceutics
A2 - Ouyang, Defang
A2 - Smith, Sean C.
PB - Wiley
CY - Chichester (UK)
ER -