TY - JOUR
T1 - Investigating the subjective cooling effect of eyelid cleansing gel on eyelid and ocular surface temperature
AU - Bilkhu, Paramdeep S
AU - Wolffsohn, James
AU - Mahmood, Qasim
AU - Purslow, Christine
N1 - © 2018, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/
PY - 2018/12/7
Y1 - 2018/12/7
N2 - Purpose
To investigate if the application of Blephagel, an eyelid cleansing gel, causes subjective and/or objective cooling effects by measuring ocular symptomology and temperature.
Methods
Twenty-five healthy subjects underwent baseline non-invasive temperature measurements on the closed upper eyelid (centrally, nasally, and temporally) and ocular surface temperature (OST) on both eyes using an infrared camera. A standard application of Blephagel was then applied to the closed upper eyelid and eyelashes with a sterile cotton-wool to one eye selected at random. Temperature measures were then repeated on both eyes after 30–60, 120–150, and 180–210 s. At each interval, subjects rated the comfort and any cooling sensation of each eye on a 0–10 scale.
Results
After application of the gel, there was a significant difference in temperature at all locations on the eyelid between the test and control eyes over time (F = 9.322, p < 0.001). Post hoc analysis revealed this was significant from 30 to 60 s interval (36.3 ± 1.1 °C versus 37.2 ± 0.7 °C; p < 0.001) and the 120–150 s interval (36.8 ± 0.8 °C versus 37.2 ± 0.6 °C; p < 0.001). There was no significant variation between the OST locations over time (F = 3.350, p = 0.07). With respect to symptoms, there was a significant increase in cooling sensation in the test eye compared to the control eye over time (F = 10.438, p < 0.001), that remained throughout the experiment.
Conclusions
Blephagel produces a reduction in temperature of the eyelids that is accompanied with a subjective cooling sensation.
AB - Purpose
To investigate if the application of Blephagel, an eyelid cleansing gel, causes subjective and/or objective cooling effects by measuring ocular symptomology and temperature.
Methods
Twenty-five healthy subjects underwent baseline non-invasive temperature measurements on the closed upper eyelid (centrally, nasally, and temporally) and ocular surface temperature (OST) on both eyes using an infrared camera. A standard application of Blephagel was then applied to the closed upper eyelid and eyelashes with a sterile cotton-wool to one eye selected at random. Temperature measures were then repeated on both eyes after 30–60, 120–150, and 180–210 s. At each interval, subjects rated the comfort and any cooling sensation of each eye on a 0–10 scale.
Results
After application of the gel, there was a significant difference in temperature at all locations on the eyelid between the test and control eyes over time (F = 9.322, p < 0.001). Post hoc analysis revealed this was significant from 30 to 60 s interval (36.3 ± 1.1 °C versus 37.2 ± 0.7 °C; p < 0.001) and the 120–150 s interval (36.8 ± 0.8 °C versus 37.2 ± 0.6 °C; p < 0.001). There was no significant variation between the OST locations over time (F = 3.350, p = 0.07). With respect to symptoms, there was a significant increase in cooling sensation in the test eye compared to the control eye over time (F = 10.438, p < 0.001), that remained throughout the experiment.
Conclusions
Blephagel produces a reduction in temperature of the eyelids that is accompanied with a subjective cooling sensation.
UR - https://linkinghub.elsevier.com/retrieve/pii/S136704841830897X
U2 - 10.1016/j.clae.2018.12.001
DO - 10.1016/j.clae.2018.12.001
M3 - Article
JO - Contact Lens and Anterior Eye
JF - Contact Lens and Anterior Eye
SN - 1367-0484
ER -