Investigation of blood microcirculation parameters in patients with rheumatic diseases by videocapillaroscopy and laser Doppler flowmetry during cold pressor test

Dmitry D. Stavtsev*, Mikhail V. Volkov, Nikita B. Margaryants, Andrey V. Potemkin, Viktor V. Dremin, Igor O. Kozlov, Irina N. Makovik, Evgeny A. Zherebtsov, Andrey V. Dunaev

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

Abstract

Videocapillaroscopy (VCS) and laser Doppler flowmetry (LDF) are non-invasive methods for evaluating microcirculation parameters. The VCS method is based on a high-speed video recording of capillaries in the nailfold. The recorded video frames are processed using a specialized algorithm to determine the red blood cells velocity. The LDF technique is based on the analysis of the Doppler shift of back-scattered laser radiation from moving red blood cells. In this work, simultaneous measurements of VCS and LDF have been performed in healthy volunteers and rheumatic patient. The study was conducted using a cold pressor test. Changes were recorded in response to cold exposure in rheumatic diseases.

Original languageEnglish
Article number110650T
JournalProceedings of SPIE - International Society for Optical Engineering
Volume11065
DOIs
Publication statusPublished - 3 Jun 2019
EventSaratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine, SFM 2018 - Saratov, Russian Federation
Duration: 24 Sep 201828 Sep 2018

Bibliographical note

Copyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Keywords

  • Cold pressor test
  • Laser Doppler flowmetry
  • Microcirculation
  • Rheumatic diseases
  • Velocity of capillary blood flow
  • Videocapillaroscopy

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