Investigation of blood microcirculation parameters in patients with rheumatic diseases by videocapillaroscopy and laser Doppler flowmetry during cold pressor test

Dmitry D. Stavtsev; Mikhail V. Volkov; Nikita B. Margaryants; Andrey V. Potemkin; Viktor V. Dremin; Igor O. Kozlov; Irina N. Makovik; Evgeny A. Zherebtsov; Andrey V. Dunaev

doi:10.1117/12.2523190

Investigation of blood microcirculation parameters in patients with rheumatic diseases by videocapillaroscopy and laser Doppler flowmetry during cold pressor test

Dmitry D. Stavtsev^*, Mikhail V. Volkov, Nikita B. Margaryants, Andrey V. Potemkin, Viktor V. Dremin, Igor O. Kozlov, Irina N. Makovik, Evgeny A. Zherebtsov, Andrey V. Dunaev

^*Corresponding author for this work

Aston Institute of Photonic Technologies (AiPT)

Research output: Contribution to journal › Conference article › peer-review

4 Citations (Scopus)

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Abstract

Videocapillaroscopy (VCS) and laser Doppler flowmetry (LDF) are non-invasive methods for evaluating microcirculation parameters. The VCS method is based on a high-speed video recording of capillaries in the nailfold. The recorded video frames are processed using a specialized algorithm to determine the red blood cells velocity. The LDF technique is based on the analysis of the Doppler shift of back-scattered laser radiation from moving red blood cells. In this work, simultaneous measurements of VCS and LDF have been performed in healthy volunteers and rheumatic patient. The study was conducted using a cold pressor test. Changes were recorded in response to cold exposure in rheumatic diseases.

Original language	English
Article number	110650T
Journal	Proceedings of SPIE - International Society for Optical Engineering
Volume	11065
DOIs	https://doi.org/10.1117/12.2523190
Publication status	Published - 3 Jun 2019
Event	Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine, SFM 2018 - Saratov, Russian Federation Duration: 24 Sept 2018 → 28 Sept 2018

Bibliographical note

Copyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Funding

The research was supported by the grant of the RFBR-r_a (project 17-41-590560) in respect of the design and assembling of the experimental setup; by the grant of the President of the Russian Federation for state support of young Russian scientists № MK-3400.2018.8 in respect of conducting of the experiments; by Ministry of Science and Higher Education of the Russian Federation (Project No. 8.2501.2017/4.6) in respect of the design of the method and algorithm of VCS data processing and by the Russian Science Foundation (the research project 18-79-00237) in respect of LDF data processing and analysis, formulation of conclusions.

Keywords

Cold pressor test
Laser Doppler flowmetry
Microcirculation
Rheumatic diseases
Velocity of capillary blood flow
Videocapillaroscopy

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10.1117/12.2523190

Investigation of blood microcirculation parameters
Copyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Final published version, 6.88 MB

Cite this

Stavtsev, D. D., Volkov, M. V., Margaryants, N. B., Potemkin, A. V., Dremin, V. V., Kozlov, I. O., Makovik, I. N., Zherebtsov, E. A., & Dunaev, A. V. (2019). Investigation of blood microcirculation parameters in patients with rheumatic diseases by videocapillaroscopy and laser Doppler flowmetry during cold pressor test. Proceedings of SPIE - International Society for Optical Engineering, 11065, Article 110650T. https://doi.org/10.1117/12.2523190

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abstract = "Videocapillaroscopy (VCS) and laser Doppler flowmetry (LDF) are non-invasive methods for evaluating microcirculation parameters. The VCS method is based on a high-speed video recording of capillaries in the nailfold. The recorded video frames are processed using a specialized algorithm to determine the red blood cells velocity. The LDF technique is based on the analysis of the Doppler shift of back-scattered laser radiation from moving red blood cells. In this work, simultaneous measurements of VCS and LDF have been performed in healthy volunteers and rheumatic patient. The study was conducted using a cold pressor test. Changes were recorded in response to cold exposure in rheumatic diseases.",

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note = "Copyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. ; Saratov Fall Meeting 2018: Optical and Nano-Technologies for Biology and Medicine, SFM 2018 ; Conference date: 24-09-2018 Through 28-09-2018",

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Stavtsev, DD, Volkov, MV, Margaryants, NB, Potemkin, AV, Dremin, VV, Kozlov, IO, Makovik, IN, Zherebtsov, EA & Dunaev, AV 2019, 'Investigation of blood microcirculation parameters in patients with rheumatic diseases by videocapillaroscopy and laser Doppler flowmetry during cold pressor test', Proceedings of SPIE - International Society for Optical Engineering, vol. 11065, 110650T. https://doi.org/10.1117/12.2523190

Investigation of blood microcirculation parameters in patients with rheumatic diseases by videocapillaroscopy and laser Doppler flowmetry during cold pressor test. / Stavtsev, Dmitry D.; Volkov, Mikhail V.; Margaryants, Nikita B. et al.
In: Proceedings of SPIE - International Society for Optical Engineering, Vol. 11065, 110650T, 03.06.2019.

Research output: Contribution to journal › Conference article › peer-review

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AU - Volkov, Mikhail V.

AU - Margaryants, Nikita B.

AU - Potemkin, Andrey V.

AU - Dremin, Viktor V.

AU - Kozlov, Igor O.

AU - Makovik, Irina N.

AU - Zherebtsov, Evgeny A.

AU - Dunaev, Andrey V.

N1 - Copyright 2019 SPIE. One print or electronic copy may be made for personal use only. Systematic reproduction, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

PY - 2019/6/3

Y1 - 2019/6/3

N2 - Videocapillaroscopy (VCS) and laser Doppler flowmetry (LDF) are non-invasive methods for evaluating microcirculation parameters. The VCS method is based on a high-speed video recording of capillaries in the nailfold. The recorded video frames are processed using a specialized algorithm to determine the red blood cells velocity. The LDF technique is based on the analysis of the Doppler shift of back-scattered laser radiation from moving red blood cells. In this work, simultaneous measurements of VCS and LDF have been performed in healthy volunteers and rheumatic patient. The study was conducted using a cold pressor test. Changes were recorded in response to cold exposure in rheumatic diseases.

AB - Videocapillaroscopy (VCS) and laser Doppler flowmetry (LDF) are non-invasive methods for evaluating microcirculation parameters. The VCS method is based on a high-speed video recording of capillaries in the nailfold. The recorded video frames are processed using a specialized algorithm to determine the red blood cells velocity. The LDF technique is based on the analysis of the Doppler shift of back-scattered laser radiation from moving red blood cells. In this work, simultaneous measurements of VCS and LDF have been performed in healthy volunteers and rheumatic patient. The study was conducted using a cold pressor test. Changes were recorded in response to cold exposure in rheumatic diseases.

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ER -

Investigation of blood microcirculation parameters in patients with rheumatic diseases by videocapillaroscopy and laser Doppler flowmetry during cold pressor test

Abstract

Bibliographical note

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Keywords

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