The integration of multiple optical techniques within a single diagnostic device is used to address the difficulties in standardising measurement of cutaneous blood micro-dynamics caused by high variability. We demonstrate the benefits of simultaneous assessment of blood relative volume (Vb), microcirculation index (Im) and tissue oxygen saturation (S tO2), during long-term examination of healthy volunteers. Consequently, five rhythmic components: endothelial, neurogenic, myogenic, breath and heart pulses were established showing high variability up to 30 - 50% as well as in initial parameters around 16%. All rhythmic components were synchronous with some latency between Im and StO 2 in the myogenic component supports the hypothesis of strong correlation between peripheral hemodynamics and oxygen utilisation in tissues.
|Journal||Proceedings of SPIE - International Society for Optical Engineering|
|Publication status||Published - 22 Mar 2013|
|Event||Advanced Biomedical and Clinical Diagnostic Systems XI - San Francisco, CA, United States|
Duration: 3 Feb 2013 → 5 Feb 2013
- bloodflow oscillations
- laser Doppler flowmetry
- tissue reflectance oximetry