TY - JOUR
T1 - Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation
AU - Dunaev, Andrey V.
AU - Sidorov, Victor V.
AU - Stewart, Neil A.
AU - Sokolovski, Sergei G.
AU - Rafailov, Edik U.
PY - 2013/3/22
Y1 - 2013/3/22
N2 - The integration of multiple optical techniques within a single diagnostic device is used to address the difficulties in standardising measurement of cutaneous blood micro-dynamics caused by high variability. We demonstrate the benefits of simultaneous assessment of blood relative volume (Vb), microcirculation index (Im) and tissue oxygen saturation (S tO2), during long-term examination of healthy volunteers. Consequently, five rhythmic components: endothelial, neurogenic, myogenic, breath and heart pulses were established showing high variability up to 30 - 50% as well as in initial parameters around 16%. All rhythmic components were synchronous with some latency between Im and StO 2 in the myogenic component supports the hypothesis of strong correlation between peripheral hemodynamics and oxygen utilisation in tissues.
AB - The integration of multiple optical techniques within a single diagnostic device is used to address the difficulties in standardising measurement of cutaneous blood micro-dynamics caused by high variability. We demonstrate the benefits of simultaneous assessment of blood relative volume (Vb), microcirculation index (Im) and tissue oxygen saturation (S tO2), during long-term examination of healthy volunteers. Consequently, five rhythmic components: endothelial, neurogenic, myogenic, breath and heart pulses were established showing high variability up to 30 - 50% as well as in initial parameters around 16%. All rhythmic components were synchronous with some latency between Im and StO 2 in the myogenic component supports the hypothesis of strong correlation between peripheral hemodynamics and oxygen utilisation in tissues.
KW - bloodflow oscillations
KW - laser Doppler flowmetry
KW - microcirculation
KW - tissue reflectance oximetry
KW - variability
UR - http://www.scopus.com/inward/record.url?scp=84877865730&partnerID=8YFLogxK
UR - https://www.spiedigitallibrary.org/conference-proceedings-of-spie/8572/1/Laser-reflectance-oximetry-and-Doppler-flowmetry-in-assessment-of-complex/10.1117/12.2001797.short
U2 - 10.1117/12.2001797
DO - 10.1117/12.2001797
M3 - Conference article
AN - SCOPUS:84877865730
SN - 0277-786X
VL - 8572
JO - Proceedings of SPIE - International Society for Optical Engineering
JF - Proceedings of SPIE - International Society for Optical Engineering
M1 - 857205
T2 - Advanced Biomedical and Clinical Diagnostic Systems XI
Y2 - 3 February 2013 through 5 February 2013
ER -