Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation

Andrey V. Dunaev; Victor V. Sidorov; Neil A. Stewart; Sergei G. Sokolovski; Edik U. Rafailov

doi:10.1117/12.2001797

Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation

Andrey V. Dunaev
, Victor V. Sidorov
, Neil A. Stewart
, Sergei G. Sokolovski
, Edik U. Rafailov

Aston Institute of Photonic Technologies (AiPT)

University of Dundee
SPE LAZMA Ltd

Research output: Contribution to journal › Conference article › peer-review

12 Citations (Scopus)

Abstract

The integration of multiple optical techniques within a single diagnostic device is used to address the difficulties in standardising measurement of cutaneous blood micro-dynamics caused by high variability. We demonstrate the benefits of simultaneous assessment of blood relative volume (V_b), microcirculation index (I_m) and tissue oxygen saturation (S _tO₂), during long-term examination of healthy volunteers. Consequently, five rhythmic components: endothelial, neurogenic, myogenic, breath and heart pulses were established showing high variability up to 30 - 50% as well as in initial parameters around 16%. All rhythmic components were synchronous with some latency between I_m and S_tO ₂ in the myogenic component supports the hypothesis of strong correlation between peripheral hemodynamics and oxygen utilisation in tissues.

Original language	English
Article number	857205
Journal	Proceedings of SPIE - International Society for Optical Engineering
Volume	8572
DOIs	https://doi.org/10.1117/12.2001797
Publication status	Published - 22 Mar 2013
Event	Advanced Biomedical and Clinical Diagnostic Systems XI - San Francisco, CA, United States Duration: 3 Feb 2013 → 5 Feb 2013

Keywords

bloodflow oscillations
laser Doppler flowmetry
microcirculation
tissue reflectance oximetry
variability

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10.1117/12.2001797

Cite this

@article{589ee00fe50944eb8e4dc847e3b81295,

title = "Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation",

abstract = "The integration of multiple optical techniques within a single diagnostic device is used to address the difficulties in standardising measurement of cutaneous blood micro-dynamics caused by high variability. We demonstrate the benefits of simultaneous assessment of blood relative volume (Vb), microcirculation index (Im) and tissue oxygen saturation (S tO2), during long-term examination of healthy volunteers. Consequently, five rhythmic components: endothelial, neurogenic, myogenic, breath and heart pulses were established showing high variability up to 30 - 50\% as well as in initial parameters around 16\%. All rhythmic components were synchronous with some latency between Im and StO 2 in the myogenic component supports the hypothesis of strong correlation between peripheral hemodynamics and oxygen utilisation in tissues.",

keywords = "bloodflow oscillations, laser Doppler flowmetry, microcirculation, tissue reflectance oximetry, variability",

author = "Dunaev, \{Andrey V.\} and Sidorov, \{Victor V.\} and Stewart, \{Neil A.\} and Sokolovski, \{Sergei G.\} and Rafailov, \{Edik U.\}",

year = "2013",

month = mar,

day = "22",

doi = "10.1117/12.2001797",

language = "English",

volume = "8572",

journal = "Proceedings of SPIE - International Society for Optical Engineering",

issn = "0277-786X",

publisher = "Society of Photo-Optical Instrumentation Engineers (SPIE)",

note = "Advanced Biomedical and Clinical Diagnostic Systems XI ; Conference date: 03-02-2013 Through 05-02-2013",

}

Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation. / Dunaev, Andrey V.; Sidorov, Victor V.; Stewart, Neil A. et al.
In: Proceedings of SPIE - International Society for Optical Engineering, Vol. 8572, 857205, 22.03.2013.

Research output: Contribution to journal › Conference article › peer-review

TY - JOUR

T1 - Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation

AU - Dunaev, Andrey V.

AU - Sidorov, Victor V.

AU - Stewart, Neil A.

AU - Sokolovski, Sergei G.

AU - Rafailov, Edik U.

PY - 2013/3/22

Y1 - 2013/3/22

N2 - The integration of multiple optical techniques within a single diagnostic device is used to address the difficulties in standardising measurement of cutaneous blood micro-dynamics caused by high variability. We demonstrate the benefits of simultaneous assessment of blood relative volume (Vb), microcirculation index (Im) and tissue oxygen saturation (S tO2), during long-term examination of healthy volunteers. Consequently, five rhythmic components: endothelial, neurogenic, myogenic, breath and heart pulses were established showing high variability up to 30 - 50% as well as in initial parameters around 16%. All rhythmic components were synchronous with some latency between Im and StO 2 in the myogenic component supports the hypothesis of strong correlation between peripheral hemodynamics and oxygen utilisation in tissues.

AB - The integration of multiple optical techniques within a single diagnostic device is used to address the difficulties in standardising measurement of cutaneous blood micro-dynamics caused by high variability. We demonstrate the benefits of simultaneous assessment of blood relative volume (Vb), microcirculation index (Im) and tissue oxygen saturation (S tO2), during long-term examination of healthy volunteers. Consequently, five rhythmic components: endothelial, neurogenic, myogenic, breath and heart pulses were established showing high variability up to 30 - 50% as well as in initial parameters around 16%. All rhythmic components were synchronous with some latency between Im and StO 2 in the myogenic component supports the hypothesis of strong correlation between peripheral hemodynamics and oxygen utilisation in tissues.

KW - bloodflow oscillations

KW - laser Doppler flowmetry

KW - microcirculation

KW - tissue reflectance oximetry

KW - variability

UR - https://www.scopus.com/pages/publications/84877865730

UR - https://www.spiedigitallibrary.org/conference-proceedings-of-spie/8572/1/Laser-reflectance-oximetry-and-Doppler-flowmetry-in-assessment-of-complex/10.1117/12.2001797.short

U2 - 10.1117/12.2001797

DO - 10.1117/12.2001797

M3 - Conference article

AN - SCOPUS:84877865730

SN - 0277-786X

VL - 8572

JO - Proceedings of SPIE - International Society for Optical Engineering

JF - Proceedings of SPIE - International Society for Optical Engineering

M1 - 857205

T2 - Advanced Biomedical and Clinical Diagnostic Systems XI

Y2 - 3 February 2013 through 5 February 2013

ER -

Laser reflectance oximetry and Doppler flowmetry in assessment of complex physiological parameters of cutaneous blood microcirculation

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Keywords

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