Left ventricular asynchrony in patients with right bundle branch block and normal ejection fraction.

B Stegemann, H Dreger, B Ismer, G Baumann, C Melzer

Research output: Contribution to journalArticlepeer-review

Abstract

Aims
The role of right bundle branch block (RBBB) for the induction of left ventricular (LV) asynchrony is discussed controversially. The objective of this study was to assess presence and degree of LV asynchrony in patients with RBBB, left bundle branch block (LBBB), or left anterior hemiblock (LAH) and normal LV function.

Methods
We included 15 patients with RBBB, 13 patients with RBBB and concomitant LAH, 10 patients with pure LBBB, and 100 healthy controls into this study. All patients had normal LV function. Interventricular asynchrony was assessed as the difference of the right and LV ejection delay. Intraventricular delay was obtained by tissue synchronicity imaging‐guided tissue Doppler imaging measurement.

Results
Interventricular and left intraventricular asynchrony were linked to the presence of an LBBB. No left intraventricular asynchrony was noted during pure RBBB; interventricular delays were negative (aortic flow preceding pulmonary flow) in the presence of RBBB.

Conclusion
In patients with normal LV function, intraventricular asynchrony depends on the presence of an LBBB and interventricular asynchrony is inversed in the presence of RBBB.
Original languageEnglish
Pages (from-to)63-68
JournalPacing and Clinical Electrophysiology
Volume36
Issue number1
Early online date4 Nov 2012
DOIs
Publication statusPublished - Jan 2013

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