Limits to tDCS effects in language: failures to modulate word production in healthy participants with frontal or temporal tDCS

Samuel J. Westwood*, Andrew Olson, R. Chris Miall, Raffaele Nappo, Cristina Romani

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Transcranial direct current stimulation (tDCS) is a method of non-invasive brain stimulation widely used to modulate cognitive functions. Recent studies, however, suggests that effects are unreliable, small and often non-significant at least when stimulation is applied in a single session to healthy individuals. We examined the effects of frontal and temporal lobe anodal tDCS on naming and reading tasks and considered possible interactions with linguistic activation and selection mechanisms as well possible interactions with item difficulty and participant individual variability. Across four separate experiments (N, Exp 1A = 18; 1B = 20; 1C = 18; 2 = 17), we failed to find any difference between real and sham stimulation. Moreover, we found no evidence of significant effects limited to particular conditions (i.e., those requiring suppression of semantic interference), to a subset of participants or to longer RTs. Our findings sound a cautionary note on using tDCS as a means to modulate cognitive performance. Consistent effects of tDCS may be difficult to demonstrate in healthy participants in reading and naming tasks, and be limited to cases of pathological neurophysiology and/or to the use of learning paradigms.
Original languageEnglish
Pages (from-to)64-82
Number of pages19
JournalCortex
Volume86
Early online date3 Nov 2016
DOIs
Publication statusPublished - 1 Jan 2017

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Healthy Volunteers
Language
Reading
Neurophysiology
Frontal Lobe
Temporal Lobe
Linguistics
Semantics
Cognition
Learning
Transcranial Direct Current Stimulation
Brain

Bibliographical note

© 2016, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/

Keywords

  • Interference effects and tDCS
  • tDCS and language tasks
  • tDCS and picture naming
  • tDCS in control participants

Cite this

Westwood, Samuel J. ; Olson, Andrew ; Miall, R. Chris ; Nappo, Raffaele ; Romani, Cristina. / Limits to tDCS effects in language : failures to modulate word production in healthy participants with frontal or temporal tDCS. In: Cortex. 2017 ; Vol. 86. pp. 64-82.
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Limits to tDCS effects in language : failures to modulate word production in healthy participants with frontal or temporal tDCS. / Westwood, Samuel J.; Olson, Andrew; Miall, R. Chris; Nappo, Raffaele; Romani, Cristina.

In: Cortex, Vol. 86, 01.01.2017, p. 64-82.

Research output: Contribution to journalArticle

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