Lipid oxidation

Norsyahida Mohd Fauzi, Corinne M. Spickett*

*Corresponding author for this work

Research output: Chapter in Book/Published conference outputChapter (peer-reviewed)peer-review

Abstract

This chapter summarizes types of lipid oxidation – both enzymatic and non-enzymatic – and discusses reactivity, biological effects and metabolism of lipid oxidation products. Mechanistic explanations are provided for the diverse biological effects of lipid oxidation products that range from deleterious to regulatory and even to protective. Finally, analytical techniques used for detection of lipid oxidation and lipid oxidation products are discussed.
Original languageEnglish
Title of host publicationStudies on experimental toxicology and pharmacology
EditorsStephen M. Roberts, James P. Kehrer, Lars-Oliver Klotz
Place of PublicationCham (CH)
PublisherSpringer
Pages43-79
Number of pages37
ISBN (Electronic)978-3-319-19096-9
ISBN (Print)978-3-319-19095-2
DOIs
Publication statusPublished - 14 Oct 2015

Publication series

NameOxidative stress in applied basic research and clinical practice
PublisherSpringer
ISSN (Print)2197-7224

Keywords

  • oxidized phospholipids
  • chlorinated lipids
  • inflammation
  • atherosclerosis
  • lipid signalling

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