TY - JOUR
T1 - Liquid phase catalytic transfer hydrogenation of ethyl levulinate to γ-valerolactone over ZrO2/SBA-15
AU - Osatiashtiani, Amin
AU - Orr, Samantha A.
AU - Durndell, Lee J.
AU - Collado García, Irene
AU - Merenda, Andrea
AU - Lee, Adam F.
AU - Wilson, Karen
N1 - © The Royal Society of Chemistry 2022
PY - 2022/7/26
Y1 - 2022/7/26
N2 - γ-Valerolactone (GVL) is an important bio-derived platform molecule whose atom- and energy efficient, and scalable, catalytic synthesis is highly desirable. Catalytic transfer hydrogenation (CTH) of ethyl levulinate (EL) to γ-valerolactone (GVL) has been selectively performed in batch and continuous flow over ZrO2/SBA-15 solid acid catalysts. Tuning the zirconia adlayer delivered maximum CTH activity for 11.6 wt% Zr, ascribed to the optimal ratio of Lewis and Brønsted acid sites for the two-step cascade reaction. EL conversion almost doubled under flow versus batch operation, accompanied by a small rise in selectivity to GVL, tripling average GVL productivity in continuous flow (5.2 vs. 1.37 mmol g−1 h−1). Turnover frequency (TOF) is significantly improved under flow conditions (14.5 h−1) relative to batch (3.6 h−1), demonstrating the utility of flow chemistry for accelerating the manufacture of valuable bio-derived molecules.
AB - γ-Valerolactone (GVL) is an important bio-derived platform molecule whose atom- and energy efficient, and scalable, catalytic synthesis is highly desirable. Catalytic transfer hydrogenation (CTH) of ethyl levulinate (EL) to γ-valerolactone (GVL) has been selectively performed in batch and continuous flow over ZrO2/SBA-15 solid acid catalysts. Tuning the zirconia adlayer delivered maximum CTH activity for 11.6 wt% Zr, ascribed to the optimal ratio of Lewis and Brønsted acid sites for the two-step cascade reaction. EL conversion almost doubled under flow versus batch operation, accompanied by a small rise in selectivity to GVL, tripling average GVL productivity in continuous flow (5.2 vs. 1.37 mmol g−1 h−1). Turnover frequency (TOF) is significantly improved under flow conditions (14.5 h−1) relative to batch (3.6 h−1), demonstrating the utility of flow chemistry for accelerating the manufacture of valuable bio-derived molecules.
UR - https://pubs.rsc.org/en/content/articlelanding/2022/CY/D2CY00538G
U2 - https://doi.org/10.1039/D2CY00538G
DO - https://doi.org/10.1039/D2CY00538G
M3 - Article
SN - 2044-4753
VL - 12
SP - 5611
EP - 5619
JO - Catalysis Science and Technology
JF - Catalysis Science and Technology
IS - 18
ER -