Localization and functional analysis of human cortical area V5 using magneto-encephalography

S J Anderson, I E Holliday, K D Singh, G F Harding

Research output: Contribution to journalArticle

Abstract

Using a multi-channel SQUID-based neuromagnetometer, we have determined the location, temporal dynamics and functional response properties of the human homologue of the primate cortical area V5 (MT). We provide evidence that area V5 in humans is located near the occipito-temporal border in a minor sulcus immediately below the superior temporal sulcus. this area is selective for low spatial frequencies ( <or = 4.0 c/deg), responds to a wide range of temporal frequencies ( <or = 35 Hz) and shows response saturation for stimulus contrasts greater than 10%. In addition, we find that this area is not responsive to purely chromatic patterns but is responsive to motion-contrast stimuli. Our results are consistent with the hypothesis that area V5 in humans represents a stage of processing within the magnocellular pathway. We discuss our results in relation to the widespread belief that area V5 in humans is specifically concerned with motion perception.
Original languageEnglish
Pages (from-to)423-31
Number of pages9
JournalProceeding of the Royal Society: Series B
Volume263
Issue number1369
DOIs
Publication statusPublished - 22 Apr 1996

Fingerprint

Magnetoencephalography
Functional analysis
functional response
SQUIDs
dynamic response
primate
saturation
Processing
Motion Perception
processing stages
Temporal Lobe
Primates
Color
border
analysis
magnetoencephalography
color

Keywords

  • Adult
  • Animals
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Magnetoencephalography
  • Male
  • Models, Neurological
  • Motion Perception
  • Photic Stimulation
  • Primates
  • Visual Cortex

Cite this

@article{11eb3cad47db45fb975040caeebba3bc,
title = "Localization and functional analysis of human cortical area V5 using magneto-encephalography",
abstract = "Using a multi-channel SQUID-based neuromagnetometer, we have determined the location, temporal dynamics and functional response properties of the human homologue of the primate cortical area V5 (MT). We provide evidence that area V5 in humans is located near the occipito-temporal border in a minor sulcus immediately below the superior temporal sulcus. this area is selective for low spatial frequencies ( <or = 4.0 c/deg), responds to a wide range of temporal frequencies ( <or = 35 Hz) and shows response saturation for stimulus contrasts greater than 10{\%}. In addition, we find that this area is not responsive to purely chromatic patterns but is responsive to motion-contrast stimuli. Our results are consistent with the hypothesis that area V5 in humans represents a stage of processing within the magnocellular pathway. We discuss our results in relation to the widespread belief that area V5 in humans is specifically concerned with motion perception.",
keywords = "Adult, Animals, Female, Humans, Magnetic Resonance Imaging, Magnetoencephalography, Male, Models, Neurological, Motion Perception, Photic Stimulation, Primates, Visual Cortex",
author = "Anderson, {S J} and Holliday, {I E} and Singh, {K D} and Harding, {G F}",
year = "1996",
month = "4",
day = "22",
doi = "10.1098/rspb.1996.0064",
language = "English",
volume = "263",
pages = "423--31",
journal = "Proceeding of the Royal Society: Series B",
issn = "0962-8452",
publisher = "The Royal Society",
number = "1369",

}

Localization and functional analysis of human cortical area V5 using magneto-encephalography. / Anderson, S J; Holliday, I E; Singh, K D; Harding, G F.

In: Proceeding of the Royal Society: Series B, Vol. 263, No. 1369, 22.04.1996, p. 423-31.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Localization and functional analysis of human cortical area V5 using magneto-encephalography

AU - Anderson, S J

AU - Holliday, I E

AU - Singh, K D

AU - Harding, G F

PY - 1996/4/22

Y1 - 1996/4/22

N2 - Using a multi-channel SQUID-based neuromagnetometer, we have determined the location, temporal dynamics and functional response properties of the human homologue of the primate cortical area V5 (MT). We provide evidence that area V5 in humans is located near the occipito-temporal border in a minor sulcus immediately below the superior temporal sulcus. this area is selective for low spatial frequencies ( <or = 4.0 c/deg), responds to a wide range of temporal frequencies ( <or = 35 Hz) and shows response saturation for stimulus contrasts greater than 10%. In addition, we find that this area is not responsive to purely chromatic patterns but is responsive to motion-contrast stimuli. Our results are consistent with the hypothesis that area V5 in humans represents a stage of processing within the magnocellular pathway. We discuss our results in relation to the widespread belief that area V5 in humans is specifically concerned with motion perception.

AB - Using a multi-channel SQUID-based neuromagnetometer, we have determined the location, temporal dynamics and functional response properties of the human homologue of the primate cortical area V5 (MT). We provide evidence that area V5 in humans is located near the occipito-temporal border in a minor sulcus immediately below the superior temporal sulcus. this area is selective for low spatial frequencies ( <or = 4.0 c/deg), responds to a wide range of temporal frequencies ( <or = 35 Hz) and shows response saturation for stimulus contrasts greater than 10%. In addition, we find that this area is not responsive to purely chromatic patterns but is responsive to motion-contrast stimuli. Our results are consistent with the hypothesis that area V5 in humans represents a stage of processing within the magnocellular pathway. We discuss our results in relation to the widespread belief that area V5 in humans is specifically concerned with motion perception.

KW - Adult

KW - Animals

KW - Female

KW - Humans

KW - Magnetic Resonance Imaging

KW - Magnetoencephalography

KW - Male

KW - Models, Neurological

KW - Motion Perception

KW - Photic Stimulation

KW - Primates

KW - Visual Cortex

UR - http://rspb.royalsocietypublishing.org/content/263/1369/423

U2 - 10.1098/rspb.1996.0064

DO - 10.1098/rspb.1996.0064

M3 - Article

C2 - 8637924

VL - 263

SP - 423

EP - 431

JO - Proceeding of the Royal Society: Series B

JF - Proceeding of the Royal Society: Series B

SN - 0962-8452

IS - 1369

ER -