Magnetoencephalography in the study of epilepsy and consciousness

Elaine Foley, Antonella Cerquiglini, Andrea Cavanna, Mable A. Nakubulwa, Paul L. Furlong, Caroline Witton, Stefano Seri

Research output: Contribution to journalArticle

Abstract

The neural bases of altered consciousness in patients with epilepsy during seizures and at rest have raised significant interest in the last decade. This exponential growth has been supported by the parallel development of techniques and methods to investigate brain function noninvasively with unprecedented spatial and temporal resolution. In this article, we review the contribution of magnetoencephalography to deconvolve the bioelectrical changes associated with impaired consciousness during seizures. We use data collected from a patient with refractory absence seizures to discuss how spike-wave discharges are associated with perturbations in optimal connectivity within and between brain regions and discuss indirect evidence to suggest that this phenomenon might explain the cognitive deficits experienced during prolonged 3/s spike-wave discharges. © 2013 Elsevier Inc.

Original languageEnglish
Pages (from-to)38-42
Number of pages5
JournalEpilepsy and Behavior
Volume30
Early online date7 Oct 2013
DOIs
Publication statusPublished - 1 Jan 2014

Fingerprint

Magnetoencephalography
Consciousness
Epilepsy
Seizures
Absence Epilepsy
Brain
Growth

Keywords

  • Absence seizures
  • Connectivity
  • Epilepsy
  • Magnetoencephalography
  • Phase lag index

Cite this

Foley, Elaine ; Cerquiglini, Antonella ; Cavanna, Andrea ; Nakubulwa, Mable A. ; Furlong, Paul L. ; Witton, Caroline ; Seri, Stefano. / Magnetoencephalography in the study of epilepsy and consciousness. In: Epilepsy and Behavior. 2014 ; Vol. 30. pp. 38-42.
@article{26a45cf803ca4e2e92ea183809cbdbec,
title = "Magnetoencephalography in the study of epilepsy and consciousness",
abstract = "The neural bases of altered consciousness in patients with epilepsy during seizures and at rest have raised significant interest in the last decade. This exponential growth has been supported by the parallel development of techniques and methods to investigate brain function noninvasively with unprecedented spatial and temporal resolution. In this article, we review the contribution of magnetoencephalography to deconvolve the bioelectrical changes associated with impaired consciousness during seizures. We use data collected from a patient with refractory absence seizures to discuss how spike-wave discharges are associated with perturbations in optimal connectivity within and between brain regions and discuss indirect evidence to suggest that this phenomenon might explain the cognitive deficits experienced during prolonged 3/s spike-wave discharges. {\circledC} 2013 Elsevier Inc.",
keywords = "Absence seizures, Connectivity, Epilepsy, Magnetoencephalography, Phase lag index",
author = "Elaine Foley and Antonella Cerquiglini and Andrea Cavanna and Nakubulwa, {Mable A.} and Furlong, {Paul L.} and Caroline Witton and Stefano Seri",
year = "2014",
month = "1",
day = "1",
doi = "10.1016/j.yebeh.2013.09.005",
language = "English",
volume = "30",
pages = "38--42",
journal = "Epilepsy and Behavior",
issn = "1525-5050",
publisher = "Elsevier",

}

Magnetoencephalography in the study of epilepsy and consciousness. / Foley, Elaine; Cerquiglini, Antonella; Cavanna, Andrea; Nakubulwa, Mable A.; Furlong, Paul L.; Witton, Caroline; Seri, Stefano.

In: Epilepsy and Behavior, Vol. 30, 01.01.2014, p. 38-42.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Magnetoencephalography in the study of epilepsy and consciousness

AU - Foley, Elaine

AU - Cerquiglini, Antonella

AU - Cavanna, Andrea

AU - Nakubulwa, Mable A.

AU - Furlong, Paul L.

AU - Witton, Caroline

AU - Seri, Stefano

PY - 2014/1/1

Y1 - 2014/1/1

N2 - The neural bases of altered consciousness in patients with epilepsy during seizures and at rest have raised significant interest in the last decade. This exponential growth has been supported by the parallel development of techniques and methods to investigate brain function noninvasively with unprecedented spatial and temporal resolution. In this article, we review the contribution of magnetoencephalography to deconvolve the bioelectrical changes associated with impaired consciousness during seizures. We use data collected from a patient with refractory absence seizures to discuss how spike-wave discharges are associated with perturbations in optimal connectivity within and between brain regions and discuss indirect evidence to suggest that this phenomenon might explain the cognitive deficits experienced during prolonged 3/s spike-wave discharges. © 2013 Elsevier Inc.

AB - The neural bases of altered consciousness in patients with epilepsy during seizures and at rest have raised significant interest in the last decade. This exponential growth has been supported by the parallel development of techniques and methods to investigate brain function noninvasively with unprecedented spatial and temporal resolution. In this article, we review the contribution of magnetoencephalography to deconvolve the bioelectrical changes associated with impaired consciousness during seizures. We use data collected from a patient with refractory absence seizures to discuss how spike-wave discharges are associated with perturbations in optimal connectivity within and between brain regions and discuss indirect evidence to suggest that this phenomenon might explain the cognitive deficits experienced during prolonged 3/s spike-wave discharges. © 2013 Elsevier Inc.

KW - Absence seizures

KW - Connectivity

KW - Epilepsy

KW - Magnetoencephalography

KW - Phase lag index

UR - http://www.scopus.com/inward/record.url?scp=84888435574&partnerID=8YFLogxK

UR - https://www.sciencedirect.com/science/article/pii/S1525505013004666?via%3Dihub

U2 - 10.1016/j.yebeh.2013.09.005

DO - 10.1016/j.yebeh.2013.09.005

M3 - Article

VL - 30

SP - 38

EP - 42

JO - Epilepsy and Behavior

JF - Epilepsy and Behavior

SN - 1525-5050

ER -