Masked comparison of two silicone hydrogel bandage contact lenses after photorefractive keratectomy

Homa Bagherian, Siamak Zarei-Ghanavati, Hamed Momeni-Moghaddam*, James S. Wolffsohn, Mohammad Reza Sedaghat, Shehzad A. Naroo, Naeemeh Monfared

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Purpose: To compare the efficiency and safety of two bandage contact lenses after photorefractive keratectomy (PRK). Methods: In this double-blind study, 45 patients (90 eyes) received PRK in both eyes and wore bandage contact lenses (BCLs), PureVision (Bausch & Lomb, Rochester, NY, USA) in one eye and PureVision2 (Bausch & Lomb, Rochester, NY, USA) in the other eye, randomly assigned. The medication regimen after surgery was the same for both eyes. The epithelial defect's size, conjunctival hyperemia and lens centration were graded objectively using slit-lamp biomicroscopy on days 1, 3 and 5 after surgery. Also ocular symptoms of discomfort including tearing, photophobia, foreign body sensation and visual fluctuations were assessed subjectively at each visit. Results: The mean epithelial defect size on the first day after operation was similar in eyes fitted with PureVision (30.08 ± 5.30 mm²) and PureVision2 (30.25 ± 5.72 mm2) lenses. (p = 0.79) Contact lens deposits and bulbar hyperaemia on days 1 and 3 after PRK were similar between the two eyes, but were significantly greater on day 5 for PureVision2 lenses. (p = 0.02; p = 0.04 respectively) There was no difference in contact lens decentration, and discomfort symptoms including pain, tearing, foreign body sensation, photophobia and visual fluctuations between the eyes fitted with PureVision and PureVision2. (p > 0.05) Conclusions: PureVision and PureVision2 contact lenses are equivalent as bandage lenses in important aspects such as corneal re-epithelialization and subjective comfort., although PureVision2 led to a higher incidence of contact lens deposits and conjunctival hyperemia early post-PRK.

Original languageEnglish
Pages (from-to)244-249
Number of pages6
JournalContact Lens and Anterior Eye
Issue number3
Early online date23 Feb 2020
Publication statusPublished - Jun 2020

Bibliographical note

© 2020, Elsevier. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International


  • Balafilcon A
  • Bandage contact lens
  • Photorefractive keratectomy PRK
  • Silicone hydrogel


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