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Mechanism of induction of muscle protein loss by hyperglycaemia
Steve T. Russell
, Seema Rajani
, Raj S. Dhadda
, Michael J. Tisdale
Aston Pharmacy School
College of Health and Life Sciences
Research output
:
Contribution to journal
›
Article
›
peer-review
69
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Citations (SciVal)
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Keyphrases
Protein Degradation
100%
Muscle Protein
100%
Hyperglycemia
100%
High Glucose
100%
Protein Loss
100%
Reactive Oxygen Species Production
75%
Protein Synthesis
75%
Eukaryotic Initiation Factor
75%
Phosphorylation
50%
Caspase-3
50%
Myotubes
50%
P38 Mitogen-activated Protein Kinase (p38 MAPK)
50%
Antioxidant
25%
Autophosphorylation
25%
Muscle Atrophy
25%
Ubiquitin-proteasome System
25%
Diabetic
25%
Gastrocnemius
25%
Glucose Effect
25%
Caspase Inhibitor
25%
Mitogen-activated Protein Kinase
25%
Induced Activation
25%
Increased Activity
25%
Butylated Hydroxytoluene
25%
Double-stranded RNA-dependent Protein Kinase
25%
SB203580
25%
MAPK Inhibitors
25%
Biochemistry, Genetics and Molecular Biology
Eukaryotic Initiation Factor
100%
Protein Biosynthesis
100%
Protein Catabolism
100%
Hyperglycemia
100%
Caspase 3
66%
Autophosphorylation
33%
Protein Kinase R
33%
Caspase
33%
Glucose Level
33%
Ob/Ob Mouse
33%
extracellular signal regulated kinase
33%
Protein Degradation
33%